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Objective: To develop and internally validate a Free Sugars Screener (FSS) for Australian children aged 2 and 5 years.
Design: Using data collected from a ninety-nine-item (2-year-olds) and ninety-eight-item (5-year-olds) FFQ in the Study of Mothers' and Infants' Life Events affecting oral health (SMILE-FFQ), a regression-based prediction modelling approach was employed to identify a subset of items that accurately estimate total free sugars intake (FSI). The predictors were grams of free sugars (FSg) for individual items in the SMILE-FFQ and child's age and sex. The outcome variable was total FSI per person. To internally validate the SMILE-FSS items, the estimated FSg was converted to percent energy from free sugars (%EFS) for comparison to the WHO free sugars guideline categories (< 5 %, 5-< 10 % and ≥ 10 %EFS) using cross-classification analysis.
Setting: Australia.
Participants: 858 and 652 2- and 5-year-old children, respectively, with complete dietary (< 5 % missing) and sociodemographic data.
Results: Twenty-two and twenty-six items were important in predicting FSI at 2 and 5 years, respectively. Items were similar between ages with more discretionary beverage items (e.g. sugar-sweetened beverages) at 5 years. %EFS was overestimated by 4·4 % and 2·6 %. Most children (75 % and 82 %) were categorised into the same WHO free sugars category with most (87 % and 95 %) correctly identified as having < 10 %EFS in line with the WHO recommendation.
Conclusions: The SMILE-FSS has good internal validity and can be used in research and practice to estimate young Australian children's FSI and compare to the WHO free sugars guidelines to identify those 'at risk'.
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http://dx.doi.org/10.1017/S1368980023002380 | DOI Listing |
J Eval Clin Pract
September 2025
Health Technology Assessment Unit, Acute and Hospital-Based Care Portfolio, Ontario Health, Toronto, Ontario, Canada.
Rationale: Systematic reviews are essential for evidence-based healthcare decision-making. While it is relatively straightforward to quantitatively assess random errors in systematic reviews, as these are typically reported in primary studies, the assessment of biases often remains narrative. Primary studies seldom provide quantitative estimates of biases and their uncertainties, resulting in systematic reviews rarely including such measurements.
View Article and Find Full Text PDFPhytopathology
September 2025
College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China.
Fusarium crown rot (FCR) is a soilborne disease that occurs in many cereal-growing regions in the world. An association between FCR development and drought stress has long been known. The FCR symptoms are pronounced under drought stress in both fields and controlled environments.
View Article and Find Full Text PDFPhysiol Plant
September 2025
Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Stress, Development and Signaling in Plants, Estación Experimental del Zaidín, Spanish National Research Council (CSIC), Granada, Spain.
Waterlogging, increasingly intensified by climate change, limits oxygen availability in the root zone, disrupting carbon and sugar metabolism, leading to energy deficits and oxidative stress that ultimately impair plant growth and productivity. Melatonin, a versatile signaling molecule, mitigates waterlogging-induced stress by enhancing anaerobic respiration and fermentation under oxygen-deprived conditions, upregulating stress-responsive genes, and restoring energy balance through optimized sugar metabolism. It also reduces oxidative damage by strengthening the antioxidant defense system and further improves stress tolerance by modulating phytohormone signaling and influencing rhizosphere microbiome dynamics.
View Article and Find Full Text PDFChem Senses
September 2025
Rutgers University Department of Nutritional Sciences. 65 Dudley Road, New Brunswick, NJ 08901, USA.
Recent research has shown that KATP channels in mouse taste bud cells enhance glucose taste signaling by depolarizing the cell when ATP is present. Relatedly, estradiol has been shown to enhance glucose sensing in human pancreatic β cells via closure of KATP channels. Since taste tissue has estradiol receptors, we linked these two observations and tested whether elevated estradiol may also enhance taste sensitivity and liking for glucose in humans.
View Article and Find Full Text PDFFood Chem
August 2025
Beijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing 100048, China. Electronic address:
Yunnan coffee is praised for the sweet caramel aroma and slightly sour taste, but its key flavor compounds and aroma formation mechanisms remain unclear. In this study, the dynamic changes of coffee aroma, amino acids, free fatty acids, free sugars, chlorogenic acids and caffeine at different roasting degrees were investigated by SAFE-GC-MS and HPLC. Roasted coffees exhibited richer flavor profiles, especially caramel, nutty and roasted flavors, while the grassy, cereal and beany flavors of green beans (GB) were significantly diminished.
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