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Background: The increasing number of total ankle arthroplasties (TAAs) has led to growing evidence on the risk factors for complications after surgery. However, the role of obesity in this patient group has been the subject of much debate. Therefore, this systematic review aimed to investigate the evidence for untoward effects of obesity following TAA.
Methods: We conducted a comprehensive search on April 28, 2023, in MEDLINE (via PubMed), Embase, and CENTRAL. Eligible observational studies reported on the short- and long-term outcomes of primary TAA, comparing patients with and without obesity (defined as body mass index > 30). Using a random effects model, we calculated pooled odds ratios (ORs) with 95% confidence intervals (CIs) from 2 by 2 tables (event and nonevent in the obese and nonobese primary TAA groups).
Results: Nine studies with 10 388 patients were eligible for inclusion in the meta-analysis. We found significantly higher odds of revision in the obese group compared to the nonobese group (OR = 1.68, CI: 1.44-1.95). However, the odds of overall perioperative complications (OR = 1.55, CI: 0.50-4.80) and wound complications (OR = 1.34, CI: 0.29-6.20) were nonsignificantly higher in the obese group.
Conclusion: Based on our results, obesity may have affected long-term outcomes following TAA and may have negatively affected the prosthesis's survival.
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http://dx.doi.org/10.1177/10711007231201158 | DOI Listing |
World J Surg
September 2025
Centre for Trauma Sciences, Blizzard Institute, Queen Mary University of London, London, UK.
Background: Penetrating injury is a time-critical disease where early definitive treatment is lifesaving. Although most patients with penetrating trauma reach the emergency department (ED) via emergency medical services (EMS), self-presentation or transport with police are also common. This review synthesizes the available evidence in adult penetrating trauma to evaluate if the mode of transport to hospital impacts early mortality.
View Article and Find Full Text PDFContact Dermatitis
September 2025
National Allergy Research Centre, Department of Dermatology and Allergy, Herlev and Gentofte Hospital, Denmark.
Rubber accelerators are chemicals used as vulcanizers in the production of rubber items and may cause contact allergy (CA). The aim of this study was to assess the worldwide prevalence of CA to rubber accelerators from the European baseline series among dermatitis patients. A comprehensive literature search across PubMed, Embase, and Web of Science yielded 106 studies with 826 543 individuals patch tested between 1984 and 2023.
View Article and Find Full Text PDFInt J Epidemiol
August 2025
Department of Infectious Disease Epidemiology and Dynamics, London School of Hygiene & Tropical Medicine, London, United Kingdom.
Background: The relationship between nutritional status and tuberculosis is critically important but poorly understood. We extended a 2009 review characterizing the relationship between body mass index (BMI) and tuberculosis risk.
Methods: We systematically searched for new studies published between 2009 and 2024 investigating BMI and tuberculosis risk in adults.
J Relig Health
September 2025
U.O.C. di Oncologia Medica con Hospice, Dipartimento di Patologia Umana, DETEV, Azienda Ospedaliera Universitaria "G. Martino", Via Consolare Valeria, 1, 98124, Messina, Italy.
Spiritual support is increasingly recognized as a vital component of psychological care in palliative settings, yet its impact on emotional recovery is not fully established. The objective is to systematically review the benefits of integrating spiritual support into psychotherapy for improving emotional recovery in palliative care. A systematic search of PubMed, Web of Science, and Embase was conducted (September 1-10, 2024) with no date limits.
View Article and Find Full Text PDFSurg Endosc
September 2025
Department of Digestive Medicine Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, 518107, People's Republic of China.
Background: Laparoscopic segmental resection (LSR) is a common treatment modality for endoscopically unresectable colorectal polyps. Laparoscopic endoscopic cooperative surgery (LECS) has emerged as a promising alternative, yet current evidence of its efficacy remains limited.
Objectives: This meta-analysis aims to compare the therapeutic outcomes of LECS versus LSR for endoscopically unresectable colorectal polyps and to provide robust evidence for clinical practice.