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http://dx.doi.org/10.1002/art.42739 | DOI Listing |
J Obes Metab Syndr
September 2025
Center of Excellence in Digestive diseases and Gastroenterology Unit, Department of Medicine, Thammasat University, Pathumthani, Thailand.
Background: The gut microbiota plays a vital role in various physiological processes, including metabolism. Fecal microbiota transplantation (FMT) involves transferring fecal matter from a healthy donor to rebalance a patient's intestinal dysbiosis. The impact of FMT on metabolic syndrome (MetS) is subject to debate.
View Article and Find Full Text PDFDiabetes Metab Res Rev
September 2025
Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Aim: Our aim was to ascertain whether metformin can reduce insulin requirement without compromising glycaemic control during pregnancy in women with type 1 diabetes.
Methods: A total of 126 pregnant women with type 1 diabetes were recruited for a randomised, double-blind, placebo-controlled multicentre study. The primary outcome was total insulin change, defined as the difference between baseline and third trimester maximum insulin dose (IU).
Lancet Rheumatol
September 2025
Bristol Royal Hospital for Children and Translational Health Sciences, Bristol, UK. Electronic address:
Background: Baricitinib has previously been shown to improve clinical response in patients with juvenile idiopathic arthritis (JIA) in the JUVE-BASIS trial. In this post-hoc analysis we aimed to identify whether pharmacodynamic changes in serum biomarkers in response to baricitinib treatment could help reaffirm the clinical utility of baricitinib in patients with JIA.
Methods: JUVE-BASIS was a randomised, double-blind, placebo-controlled, withdrawal, efficacy, safety, phase 3 trial, done in 75 centres in 20 countries.
Lancet Rheumatol
September 2025
National Institute for Health and Care Research Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK. Electronic address:
Background: The optimal treatment strategy in early psoriatic arthritis remains unknown. We aimed to assess whether the combination of methotrexate and golimumab plus corticosteroids is superior to methotrexate plus corticosteroids in reducing disease activity in early, untreated psoriatic arthritis.
Methods: We did a double-blind, randomised, placebo-controlled, parallel-group, single-centre study in adults with treatment-naïve active psoriatic arthritis.
Acta Psychol (Amst)
September 2025
Department of Psychology, Chung-Shan Medical University, Taichung, Taiwan; Clinical Psychological Room, Chung-Shan Medical University Hospital, Taichung, Taiwan. Electronic address:
Background: Previous research indicates near transfer effects of working memory (WM) training on updating, shifting, and inhibition tasks, although findings vary. Regarding fluid intelligence (Gf), studies yield conflicting results on the far transfer effects of WM training. The current study investigates whether different styles of adaptive visuospatial N-back WM training produce near and far transfer effects and whether individual differences moderate these effects.
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