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http://dx.doi.org/10.1093/ije/dyad137 | DOI Listing |
J Neurosurg Sci
September 2025
Department of Neurological Surgery, University of Rochester Medical Center, Rochester, NY, USA.
Background: Symptomatic lumbar degenerative changes impact millions of patients per year. Recent technological advances have increased the usability of robot-assisted spinal fusions to treat this pathology. Although the safety profile of robotic systems appears favorable, the impact of robotics on surgical outcomes and efficiency remains unclear.
View Article and Find Full Text PDFAnn Neurol
September 2025
Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA.
Objective: The objective of this study was to compare the long-term safety profiles of ocrelizumab and rituximab in persons with multiple sclerosis (MS).
Methods: Using retrospective data from the University of California (UC) Health System, we simulated a target clinical trial. The primary cohort from UC San Francisco (UCSF) and a validation cohort from 5 other UC Medical Centers were analyzed.
Liver Int
October 2025
Division of Gastroenterology and Hepatology, Department of Medicine, The Institute for Bioelectronic Medicine, Feinstein Institutes for Medical Research & Cold Spring Harbor Laboratory, Northwell Health, Manhasset, New York, USA.
Background: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths, primarily due to late-stage diagnosis. In this multicenter study, our goal is to identify functional biomarkers that stratify the risk of HCC in patients with cirrhosis (CP) for early diagnosis.
Methods: Five thousand and eight serum proteins (Somascan) were analysed in Cohort A (477 CP, including 125 HCC).
Diabetes Obes Metab
September 2025
Department of Applied Health Sciences, University of Birmingham, Birmingham, UK.
Aim: Sodium-glucose co-transporter-2 inhibitors (SGLT2i) offer significant cardiorenal benefits for people with type 2 diabetes (PwT2D). However, concerns remain regarding their association with diabetes-related ketoacidosis (DKA). (1) To compare demographics, precipitating factors, biochemical features, management, and outcomes of acute DKA admissions between SGLT2i users (n = 267) and non-users (n = 793) with T2D.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
September 2025
Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, People's Republic of China.
Objective: Adolescent anhedonia (AA) exhibits distinct characteristics. Currently available anhedonia scales in Chinese are designed solely for adult populations. This investigation assessed the psychometric characteristics of the Chinese Anhedonia Scale for Adolescents (ASA-C) across clinical, subthreshold, and typically developing adolescent cohorts, while establishing its optimal cut-off for prominent anhedonia identification.
View Article and Find Full Text PDF