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Inositols are insulin-sensitizing compounds of promising efficacy in the management of polycystic ovary syndrome (PCOS). On the one hand, myo-inositol (myo-ins) plays a regulatory role in male and female reproductive function, influencing the development of oocytes, spermatozoa, and embryos. On the other hand, high concentrations of D-chiro-inositol (D-chiro-ins) in the ovary may adversely affect oocyte quality. This review analyses the available literature, which encourages the clinical use of myo-ins in assisted reproductive technologies (ARTs) due to its beneficial effects on female and male reproduction.
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http://dx.doi.org/10.1016/j.tem.2023.09.005 | DOI Listing |
Development
September 2025
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.
In an era of expanding reproductive possibilities, the human embryo has come to represent both immense potential and profound constraint. Advances in medically assisted reproduction (MAR) have led to the cryopreservation of hundreds of thousands of embryos each year, yet many remain unused and are ultimately discarded. Meanwhile, studies aimed at understanding infertility, early human development and preventing miscarriage continue to face significant barriers, with only a small fraction of embryos ever donated to research.
View Article and Find Full Text PDFSex Reprod Health Matters
September 2025
Senior Research Scientist, Guttmacher Institute, New York, United States.
Since the release of the Supreme Court decision in June 2022, researchers have been working to better understand the impact that the growing number of abortion restrictions are having on the provision of and access to abortion services in the United States (US). Less is known about the impact of abortion restrictions on the provision of sexual and reproductive health (SRH) services more broadly, including at clinics that do not directly offer abortion. Between November 2023 and February 2024, we conducted interviews with SRH managers, clinic managers, and other administrators at publicly funded SRH clinics around the US to generate evidence on the effects of state-level abortion restrictions on the provision of abortion and related services, such as pregnancy options counselling and abortion referrals, at facilities providing contraceptive services.
View Article and Find Full Text PDFEur J Prev Cardiol
September 2025
Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Background And Aims: Data on cardiovascular outcomes and aortic growth in pregnant women with Turner syndrome is limited. We examine the cardiovascular and pregnancy outcomes in these women and analyze aortic growth throughout pregnancy.
Methods: The ROPAC III is a global, prospective, observational registry that enrolled pregnancies of women pre-pregnancy known with Turner syndrome from 2018 to 2023.
Am J Epidemiol
September 2025
Department of Epidemiology, Harvard T.H. Chan School of Public Health.
In 2016, the NIH designated LGBTQ+ individuals (ie, lesbian, gay, bisexual, transgender, queer, and all sexual and gender minorities) as a health disparities population. The growing interest in studying the health of LGBTQ+ populations merits revisiting the methodological approaches researchers employ. We elucidate how researchers can identify appropriate adjustment sets for causal questions using directed acyclic graphs (DAGs).
View Article and Find Full Text PDFTicks Tick Borne Dis
September 2025
Department of Parasitology and Zoology, University of Veterinary Medicine, Budapest, Hungary; HUN-REN-UVMB Climate Change: New Blood-sucking Parasites and Vector-borne Pathogens Research Group, Budapest, Hungary.
The aim of this study was to assess the viability of an opportunistic population of Hyalomma rufipes, as evidence of reproduction had been documented in the southern part of Central Europe, specifically Hungary, in 2022. To assess the current situation, tick collections targeting various mammalian species were organized with the assistance of local veterinarians between September 2022 and May 2024. Over the study period, 1502 ticks were collected; however, none belonged to the Hyalomma genus.
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