Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Assessment of the risk of pesticide inhalation in populations around farmland is necessary because inhalation is one of the ways in which pesticides can risk human health. This study aimed to identify the inhalation risk of difenoconazole on humans by using dose-response and exposure assessments.
Results: In the field simulation application, respiratory exposure in populations around farmland ranged from 71 to 430 ng/m . Using response surface methodology, the maximum bioaccessibility of difenoconazole in three simulated lung fluids was 35.33% in Gamble's solution (GS), 34.12% in artificial lysosomal fluid (ALF), and 42.06% in simulated interstitial lung fluid (SLF). Taking the proliferation activity of the A549 cell model as the endpoint, the benchmark dose limit and benchmark dose of difenoconazole on A549 cells were 16.36 and 5.60 mg/kg, respectively. The margin of exposure to difenoconazole in GS, ALF and SLF were, respectively, 8.66 × 10 to 5.28 × 10 , 8.97 × 10 to 5.47 × 10 and 7.28 × 10 to 4.44 × 10 .
Conclusion: The risk assessment results indicate that under all circumstances, applying difenoconazole is safe for populations around farmland. However, a fan-shaped nozzle, suspension concentrate and greater inhalation height increase the risk of inhalation. © 2023 Society of Chemical Industry.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/ps.7811 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessing Soil Pollution Potential through Spatial Heavy Metal Bioaccessibility for Health Risk Evaluation.
Integr Environ Assess Manag
September 2025
School of Public Health, Taipei Medical University, New Taipei City, 235040Taiwan.
Incorporating bioaccessibility into health risk assessments enhances the accuracy of exposure estimates for heavy metal (HM) pollution, supports targeted remediation, and informs public health and policy decisions, particularly for vulnerable populations. Because HM bioaccessibility depends on local soil and geographic characteristics, identifying its relationship with soil properties is crucial for assessing soil pollution potential. Although HM concentrations can be measured relatively easily, bioaccessibility requires complex laboratory procedures, limiting routine applications in regulatory contexts.
View Article and Find Full Text PDFInfluence of wind direction on the relationship between proximity to pig farms and risk of infection with MRSA CC398 among persons without known contact to livestock: a Danish nationwide population-based study.
Infection
September 2025
Research Unit for Environment, Work and Health, Department of Public Health, Aarhus University, Bartholins Allé 2, Building 1260, Aarhus C, DK-8000, Denmark.
Background: Livestock-MRSA (methicillin-resistant Staphylococcus aureus) can cause infections in persons without known contact to livestock, but the route of transmission is unclear. We investigated whether the risk of livestock-MRSA infection among persons with no known contact to livestock is associated with the number of pig farms near the home, and whether this association is affected by the upwind/downwind location of the farms.
Methods: Register-based case-control study of 518 persons from Denmark with clinical infections with livestock-MRSA in 2016-2021 and no known exposure to livestock, and 4,944 matched controls.
Avian influenza spillover into poultry: environmental influences and biosecurity protections.
One Health
December 2025
U.S. Geological Survey, Eastern Ecological Science Center, Laurel, MD 20708, USA.
With the continued spread of highly pathogenic avian influenza (HPAI), understanding the complex dynamics of virus transfer at the wild - agriculture interface is paramount. Spillover events (i.e.
View Article and Find Full Text PDFProbability of Influenza A virus RNA detection at different pooling levels for commonly used sample types in swine breeding herds.
Prev Vet Med
September 2025
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States. Electronic address:
Pooling samples allows for efficient and cost-effective surveillance of endemic pathogens, enabling broader testing coverage and reducing diagnostic costs. Pooling swine samples for influenza A virus surveillance without negatively impacting sensitivity would depend on the sample type, cycle threshold (Ct value), and dilution level. Therefore, this study aimed to compare the probability of IAV reverse transcription real-time polymerase chain reaction (RT-rtPCR) detection at different pooling levels in family oral fluids, udder wipes, and nasal wipes obtained from an endemic swine breeding herd.
View Article and Find Full Text PDFUnderstanding the transmission routes of high-pathogenicity avian influenza (HPAI) is crucial for developing effective control measures to prevent its spread. In this context, windborne transmission, the idea that the virus could travel through the air over considerable distances, is a contentious concept, and documented cases have been rare. Here, though, we provide genetic evidence supporting the feasibility of windborne transmission.
View Article and Find Full Text PDF