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http://dx.doi.org/10.1016/S1473-3099(23)00437-1 | DOI Listing |
JAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.
Egypt Heart J
September 2025
Department of Cardiology, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Background: Long-term outcomes of transcatheter mitral valve edge-to-edge repair (TEER) are compared with medical therapy remain under investigation. This study evaluated the 3-year effects of MitraClip on mitral regurgitation (MR) severity, ventricular remodeling, and clinical outcomes in high surgical-risk patients.
Methods: A single-center retrospective cohort included 31 MitraClip patients (2016-2023) and 30 contemporaneous controls on maximally tolerated guideline-directed medical therapy.
J Phys Chem Lett
September 2025
Department of Materials and Mineral Resources Engineering, National Taipei University of Technology, No. 1, Section 3, Chung-Hsiao East Road, Taipei 106, Taiwan.
Sugarcane () was employed as a sustainable carbon source to synthesize three-dimensional (3D) spherical manganese carbonate (MnCO) microspheres, offering a green route to advanced electrode material for high-energy-density symmetric supercapacitors. Although numerous synthesis strategies and material modifications have been explored, a detailed evaluation of environmentally friendly synthesis pathways remains essential. In this study, MnCO microspheres were successfully synthesized via a sugar-derived green synthesis followed by hydrothermal treatment.
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
State Key Laboratory of Electrical Insulation and Power Equipment, Xi'an Jiaotong University, Xi'an 710049, China.
Economically viable and biologically compatible amino acids demonstrate significant potential as electrolyte microstructure modifiers in aqueous zinc-ion batteries (AZIBs). Compared to polar amino acids, nonpolar amino acids simultaneously own zincophilicity and hydrophobicity, showing great potential in the industrial application of AZIBs. However, nonpolar amino acids have been comparatively understudied in existing research investigations.
View Article and Find Full Text PDFCurr Opin Urol
September 2025
Department of Urology, Faculty of Medicine, University of Toyama, Toyama, Japan.
Purpose Of Review: Nonmuscle-invasive bladder cancer (NMIBC) patients with BCG-unresponsive disease have limited treatment options beyond radical cystectomy. With ongoing BCG shortages and the urgent need for bladder-preserving alternatives, this review examines the emerging role of oncolytic virus therapy as a novel intravesical treatment approach for this challenging patient population.
Recent Findings: Multiple oncolytic viral platforms have entered clinical trials for NMIBC treatment, demonstrating promising efficacy and safety profiles.