Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Melasma is a chronic hypermelanosis of the skin that affects approximately 1% of the global population, predominantly affects women, and is more prevalent in skin of color. Melasma is a common driver for patients with skin of color to seek out a dermatologist for treatment, and ensuring the right approach for these patients is important because some treatments may be associated with adverse side effects. Because of the chronicity of the disease and established psychosocial and emotional impacts, there is a large need to ensure care follows the best available evidence on the treatment of patients with melasma.

Objective: Here, we summarized current available topical treatments for melasma with considerations dermatologists should have for their patients with skin of color.

Methods: Steering committee consensus on clinical best practices.

Results: We describe a flexible and focused treatment algorithm that reflects both treatment and maintenance periods that is a consensus of our extensive clinical experience.

Limitations: Use of real-world evidence and potential for individual practice bias.

Conclusion: Melasma can be challenging to treat, particularly in patients with skin of color, and our recommendations for best practices for patients in the United States are an important step toward standardizing care.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaad.2023.07.1045DOI Listing

Publication Analysis

Top Keywords

patients skin
16
skin color
16
best practices
8
patients
7
skin
6
treatment
5
melasma
5
best
4
practices treatment
4
treatment melasma
4

Similar Publications

Ultrasonographic Analysis of Site-Specific Plantar Skin Thickness for Melanoma Staging and Excision.

Clin Anat

September 2025

Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.

Plantar melanomas present unique diagnostic and surgical challenges owing to substantial regional variations in skin thickness. Although the Breslow thickness remains the primary criterion for staging and surgical excision, its application on plantar melanoma is complicated by the inherent thickness of the glabrous plantar epidermis, which may lead to tumor depth overestimation. Accurate assessment of plantar skin thickness is essential for optimizing staging accuracy and refining surgical margins.

View Article and Find Full Text PDF

Background: Romosozumab is a sclerostin-inhibiting monoclonal antibody that is effective and safe for anabolic treatment in patients with osteoporosis. Its main adverse effects are local; the severity of these injection-site reactions in clinical trials was generally mild.

Case Report: We present a case of a 71-year-old Colombian woman with osteoporosis at very high risk of fractures with no relevant history of drug allergies.

View Article and Find Full Text PDF

Tahiti or the "myth of Paradise", Bora Bora, "the Pearl of the Pacific". Who has never wanted to take a plane and come and land on the heavenly beaches of Polynesia, a French territory at the antipodes of mainland France lost in the middle of the Pacific? However, we do not imagine that 60% of Polynesians live below the metropolitan low-income threshold or that life expectancy is lower than that of the mainland due to the high prevalence of cardiovascular diseases with three quarters overweight population.In addition to non-transmissible metabolic diseases, various pathologies common to temperate countries present specificities in Polynesia, leading to sometimes different management and medical reasoning.

View Article and Find Full Text PDF

The Famous Sir William Osler: A Physician Acupuncturist and His Pain.

Med Acupunct

August 2025

American TCM Association, Vienna, Virginia, USA.

Acupuncture, an integral part of traditional Chinese medicine, has been practiced for over 2,500 years. Dr. William Osler, a renowned physician in Canada and the United States during the late 1800s, was also an acupuncturist.

View Article and Find Full Text PDF

Background: Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory disease caused by a gain-of-function mutation in the gene, which regulates inflammasome-mediated interleukin-1β (IL-1β) production. This leads to recurrent episodes of fever, rash, and arthritis, typically beginning in childhood.

Objective: To demonstrate the role of a missense mutation, c.

View Article and Find Full Text PDF