Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Background: Heterotopic ossification (HO), a common complication after elbow trauma, causes severe limb disability. Resection is usually performed for posttraumatic elbow HO (PTEHO) to regain mobility, and although heavily reported, there has been no long-term (minimum, 5-year) follow-up.

Methods: A total of 173 patients who underwent PTEHO resection were followed up for a minimum of 5 years in 4 hospitals between January of 2015 and August of 2016. Demographics, disease characteristics, and preoperative and minimum 5-year assessments were collected. After controlling for potential variables when dividing long-term range of motion (ROM) into less than 120 degrees and greater than or equal to 120 degrees, risk factors for ROM recovery to modern functional arc were identified through multivariable regression analysis.

Results: Clinically important improvements in ROM from 39 degrees to 124 degrees were obtained at final follow-up, and 74.6% achieved modern functional arc (≥120 degrees). Mayo Elbow Performance Index had clinically important increases from 69 to 93 points at final follow-up, and 96.5% reported excellent to good. Pain (numeric rating scale, from 1.9 to 0.6 points) and ulnar nerve symptoms were improved. The total complication rate was 15.6%, including new-onset ulnar nerve symptoms (5.8%), HO recurrence with clinical symptoms (6.9%), elbow instability (1.7%), and joint infection (1.2%). Previously reported high body mass index ( P = 0.002) and long disease duration ( P = 0.033) were equally identified as risk factors for not achieving modern functional arc; meanwhile, tobacco use ( P = 0.024) and ankylosed HO ( P < 0.001) were found to be new risk factors.

Conclusions: Resection yields satisfactory outcomes for PTEHO at long-term follow-up of a minimum of 5 years. High body mass index, tobacco use, long disease duration, and ankylosed HO would negatively affect ROM recovery to a modern functional arc (≥120 degrees).

Clinical Question/level Of Evidence: Risk, III.

Download full-text PDF

Source
http://dx.doi.org/10.1097/PRS.0000000000011077DOI Listing

Publication Analysis

Top Keywords

modern functional
16
functional arc
16
minimum 5-year
12
posttraumatic elbow
8
heterotopic ossification
8
minimum years
8
120 degrees
8
risk factors
8
rom recovery
8
recovery modern
8

Similar Publications

Endophytic fungi are nonpathogenic fungi that live symbiotically in the interior of healthy plant tissues and form mutualistic associations with their hosts. These fungi are critically involved in promoting plant development, strengthening plant uptake of nutrients, and improving plant resistance to biotic and abiotic stress conditions. Endophytic fungi improve plant growth by synthesizing phytohormones (e.

View Article and Find Full Text PDF

Modern surgical strategies for keratoconus aim to both stabilize disease progression and correct induced refractive errors. Effectively and simultaneously achieving both goals remains a relevant challenge. This study presents a clinical case of femtosecond laser-assisted intrastromal keratoplasty with implantation of a biosynthetic complex, demonstrating the efficacy of this surgical approach in treating keratoconus.

View Article and Find Full Text PDF

Rethinking the Kohn-Sham inverse problem.

J Chem Phys

September 2025

Theoretical Physics IV, University of Bayreuth, 95447 Bayreuth, Germany.

Density functional theory (DFT) is a cornerstone of modern electronic structure theory. In the Kohn-Sham scheme, the many-electron Schrödinger equation is replaced by a set of effective single-particle equations. Thus, the full complexity of the quantum mechanical many-particle effects is mapped to the exchange-correlation potential vxc(r).

View Article and Find Full Text PDF

Mechanistic Insights and Translational Therapeutics of Neurovascular Unit Dysregulation in Vascular Cognitive Impairment.

J Integr Neurosci

August 2025

Key Laboratory of Modern Toxicology of Ministry of Education; School of Basic Medical Sciences, Nanjing Medical University, 211166 Nanjing, Jiangsu, China.

Cognitive impairment represents a progressive neurodegenerative condition with severity ranging from mild cognitive impairment (MCI) to dementia and exerts significant burdens on both individuals and healthcare systems. Vascular cognitive impairment (VCI) represents a heterogeneous clinical continuum, spanning a spectrum from subcortical ischemic VCI (featuring small vessel disease, white matter lesions, and lacunar infarcts) to mixed dementia, where vascular and Alzheimer's-type pathologies coexist. While traditionally linked to macro- and microvascular dysfunction, the mechanisms underlying VCI remain complex.

View Article and Find Full Text PDF

Modern multiple myeloma treatment enables deep and sustained responses, necessitating assessment of minimal residual disease (MRD) in the bone marrow to refine response categorization. Recently, mass spectrometry (MS)-based methods have emerged as highly sensitive tools for measuring MRD in the peripheral blood. However, the role specific MS techniques play in response categorization has yet to be established.

View Article and Find Full Text PDF