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The reality of the autonomous vehicle in a near future is growing and is expected to induce significant change inthe occupant posture with respect to a standard driving posture. The delegated driving would allow sleeping and/or resting in a seatwith a reclined posture. However, the data in the literature are rare on the body kinematics, human tolerance, and injury types insuch reclined postures. The current study aims at increasing the knowledge in the domain and providing useful data to assess therelevance of the standard injury assessment tools such as anthropomorphic test devices or finite element human body models. For that purpose, a test series of three male Post-Mortem Human Subjects (PMHS) were performed in frontal impact at a 13.4 m/sdelta V. The backseat inclination was 58 degrees with respect to the vertical axis. The semi-rigid seat developed by Uriot et al.(2015) was used with a stiffer seat ramp. The restraint was composed of a lap belt equipped with two 3.5 kN load limiters, and ofa shoulder belt equipped of a 4 kN load limiter on the upper anchorage placed in the vicinity of the shoulder. The belts, the semi-rigid seat, and the footrest were equipped with force sensors. The rotations of the seat pan and of the seat ramp were also measured. The PMHS were instrumented with multi-axis accelerometers and Y angular velocity sensors attached to the head, thorax (T1 andT12 vertebrae), and sacrum. Strain gauges were glued onto the anterior face of the L1 to L5 lumbar vertebrae and onto the anteriorface of the iliac wings. To estimate the pelvis kinematics, a rigid support equipped with targets was fixed onto the femur shaft. Prior to test, X-ray imagery was performed to exhibit the initial curvature of the lumbar spine. After the tests, an in-depth necropsywas done, with a specific attention to the lumbar spine. In the chosen test conditions, no lap-belt submarining was observed for the three PMHS. One PMHS sustained an AIS2 pelvic ringfracture and another one sustained an AIS4 injury with complete separation of the left and right sacroiliac joints. Lumbar discruptures and vertebral fractures were observed for the three PMHS (AIS 2 and AIS3 coding). The number of separated rib fractureswere very different from one PMHS to another (0, 6 and 33). Response corridors for the external forces and kinematics were builtand are presented in the paper. The results are discussed by comparing with existing data for which the backseat was in standardposture.
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http://dx.doi.org/10.4271/2022-22-0001 | DOI Listing |
J Trace Elem Med Biol
September 2025
Department of Neurobiology, Maj Institute of Pharmacology, Polish Academy of Sciences, Smętna 12, Kraków 31-343, Poland. Electronic address:
Vanadium (V) is a trace element in the environment; it is detected in soil, water, air, dust, and food products. V-containing compounds have shown therapeutic potential in the treatment of diabetes. However, studies on the effects of V on animal behavior remain limited and sporadic.
View Article and Find Full Text PDFStroke
September 2025
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China (H.Z., K.H., Q.G.).
Background: Poststroke cognitive impairment (PSCI) affects 30% to 50% of stroke survivors, severely impacting functional outcomes and quality of life. This study uses functional near-infrared spectroscopy (fNIRS) to assess task-evoked brain activation and its potential for stratifying the severity in patients with PSCI.
Method: A cross-sectional study was conducted at Nanchong Central Hospital between June 2023 and April 2024.
Brain Behav
September 2025
Centre For Cognitive and Clinical Neuroscience, College of Health, Medicine and Life Sciences, Brunel University of London, London, UK.
Introduction: There is an ongoing debate about the neural mechanisms and subjective preferences involved in the processing of social rewards compared to non-social reward types.
Methods: Using whole-brain functional magnetic resonance imaging (fMRI), we examined brain activation patterns during the anticipation and consumption phases of monetary and social rewards (using the Monetary and Social Incentive Delay Task-MSIDT, featuring human avatars) and their associations with self-reported social reward preferences measured by the Social Reward Questionnaire (SRQ) in 20 healthy right-handed individuals.
Results: In the anticipation phase, all reward types activated the dorsal striatum, middle cingulo-insular (salience) network, inferior frontal gyrus (IFG), and supplementary motor areas.
Brain Res
September 2025
Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil; Departamento de Ciências Morfológicas, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre,
It has been recently described the Congenital Zika Syndrome (CZS). Children from pregnant women who were infected by the virus have expressed a set of symptoms, particularly involving neurological disorders such as microcephaly. Animal models have been conducted aiming to enhance the knowledge about the CZS and giving support for future studies proposing prevention and treatment for this condition.
View Article and Find Full Text PDFPsychiatry Res Neuroimaging
August 2025
Faculty of Social Science, University of Ottawa, Canada.
Background: Childhood sexual abuse (CSA) can cause lasting neurodevelopmental changes, posing significant challenges for survivors. Its specific impact on men remains heavily stigmatized and under-researched. This study examined neurophysiological correlates of CSA in men using diffusion tensor imaging (DTI).
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