Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Spontaneous regression (SR) of cancer is very rare, especially of small cell lung cancer (SCLC). Recently, an association of paraneoplastic neurological syndrome (PNS) has been reported as a cause of SR of cancer, and onconeural antibodies are a possible factor in the SR of cancer associated with PNS. We herein report the first case of SR of SCLC combined with anti-P/Q-type of voltage-gated calcium channel (VGCC) antibody-positive Lambert-Eaton myasthenic syndrome (LEMS), a subtype of PNS. This case report suggests that SCLC may be spontaneously reduced by an autoimmune response induced by VGCC antibodies associated with LEMS. Our finding may help elucidate the mechanisms that inhibit tumor growth and cause the regression of tumors.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480669 | PMC |
| http://dx.doi.org/10.1016/j.radcr.2023.08.059 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative outcomes of excision and active surveillance for cervical intraepithelial neoplasia 2 in women under 35: a single institutional retrospective study.
Obstet Gynecol Sci
September 2025
Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.
Objective: This study aimed to compare the outcomes of excision (conization) and active surveillance in women under 35 years of age diagnosed with cervical intraepithelial neoplasia 2 (CIN 2) on disease regression to normal cervical cytology and the effectiveness of nonsurgical management.
Methods: This retrospective cohort study was conducted at OOO. Women under 35 diagnosed with CIN 2 were included and divided into two groups based on the management strategy: excisional treatment or active surveillance.
Obstetric and neonatal outcomes in pregnancies with familial mediterranean fever: a comparative study.
Rheumatol Int
September 2025
Division of Perinatology, Department of Obstetrics, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, Istanbul, Turkey.
Familial Mediterranean Fever (FMF) is frequently diagnosed during reproductive ages, but its impact on pregnancy remains unclear. We aimed to evaluate maternal and neonatal outcomes in FMF pregnancies by comparing before and after diagnosis periods as well as with healthy controls, and to identify predictors of adverse outcomes. This retrospective, cross-sectional study included 215 pregnancies (129 before and 86 after FMF diagnosis) from 81 women with FMF and 94 pregnancies from 42 healthy controls.
View Article and Find Full Text PDFPD-L1 neutrophils mediate immune regulation of CD8 T cells in halo nevi.
Front Immunol
September 2025
Department of Burns and Plastic Surgery, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, China.
Background: Halo nevi are clinically common and are characterized by a circle of leukoderma around the central melanocytic nevus. Studies have shown that the pathogenesis of halo nevi is similar to that of vitiligo and is associated with the role of CD8⁺ T lymphocytes in melanocyte destruction. Histopathological findings have revealed neutrophil infiltration in halo nevi; however, the specific immune mechanisms involving neutrophils have not been thoroughly investigated.
View Article and Find Full Text PDFA single-center retrospective study on clinical features and outcomes of perimesencephalic non-aneurysmal subarachnoid hemorrhage patients.
Neuroscience
September 2025
Institute of Neurology, General Hospital of Northern Theater Command, Shenyang, Liaoning 110016, China. Electronic address:
Perimesencephalic non-aneurysmal subarachnoid hemorrhage (pmSAH) is a subtype of subarachnoid hemorrhage (SAH) where the bleeding source remains unclear. It is generally associated with a benign clinical course compared to other SAH types. This study retrospectively analyzed 198 pmSAH patients admitted between January 2019 and December 2023, along with 137 non-perimesencephalic non-aneurysmal subarachnoid hemorrhage (npmSAH) and 198 aneurysmal SAH patients as controls.
View Article and Find Full Text PDFAssociation between temporalis and masseter muscle thickness and dysphagia in patients with spontaneous intracerebral hemorrhage.
J Clin Neurosci
September 2025
Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital Hsin-Chu Branch, Hsin-chu, Taiwan; Department of Physical Medicine and Rehabilitation, College of Medicine, National Taiwan University Hospital, National Taiwan University, Taiwan. Electronic address: b96401093@n
Objectives: The aim of this study is to investigate the association between masticatory muscle thickness and dysphagia in intracerebral hemorrhage (ICH) patients.
Materials & Methods: This retrospective cohort study included patients with spontaneous ICH confirmed by brain computed tomography (CT) between June 2019 and June 2024 in a university-affiliated hospital. Temporal muscle thickness (TMT) and masseter muscle thickness (MMT) were measured on the initial brain CT.