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Lower back pain is a prevalent condition affecting people across all age groups and causing significant personal and societal burdens. While numerous treatments exist, nerve mobilization has emerged as a promising approach for managing lower back pain. Nerve mobilization involves applying gentle and rhythmic movements to the affected nerves, promoting normal nerve function and releasing tension. It has been well documented that nerve mobilization can be effective in reducing pain and improving function in patients with lower back pain, but the underlying mechanisms have not been clarified. This study aims to review the mechanisms of nerve mobilization in the management of lower back pain, its application, and effectiveness evaluation, and provide a potential solution for managing lower back pain.
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http://dx.doi.org/10.1097/MD.0000000000034961 | DOI Listing |
Lung
September 2025
The Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, Belfast BT9 7BL, UK.
Introduction: Rhinovirus (RV) is the leading cause of exacerbations of lung disease. A sensory neuronal model, derived from human dental pulp stem cells and differentiated into peripheral neuronal equivalents (PNEs), was used to examine RV's effects on airway sensory nerves. We investigated whether RV can directly infect and alter PNEs or whether it exerts effects indirectly via the release of mediators from infected epithelial cells.
View Article and Find Full Text PDFBone Jt Open
September 2025
School of Medicine, University of Nottingham, Nottingham, UK.
Aims: The number of hip fractures is increasing, with significant mortality and morbidity, particularly among frail and comorbid patients. Enhanced recovery after surgery (ERAS) pathways have proven effective in elective orthopaedics, but this has not been investigated in people with hip fractures. This study aimed to identify current perioperative practice and develop a cohesive ERAS pathway tailored for hip fracture patients, to standardize and optimize care.
View Article and Find Full Text PDFJ Orthop
December 2025
Department of Palliative Medicine, Poznan University of Medical Sciences, Poland.
Background: Total hip arthroplasty (THA) is associated with significant postoperative pain, which can impair early mobilization and recovery. Erector spinae plane block (ESPB) has emerged as a promising regional anesthesia technique for lower limb surgeries. However, the duration of single-shot ESPB is limited.
View Article and Find Full Text PDFCardiovasc Intervent Radiol
August 2025
Department of Vascular and Oncological Interventional Radiology, Hôpital Européen Georges Pompidou, APHP, Paris, France.
Purpose: The study reports the initial experience in transarterial embolization (TAE) using an ethiodized oil-based emulsion for patients with refractory shoulder pain, focusing on safety, pain reduction, and functional improvement.
Methods: This is a retrospective, multicenter study including 23 patients treated with TAE using an ethiodized oil-based emulsion between April 2021 and May 2024. Clinical outcomes were assessed using visual analog scale (VAS) scores for pain (0-100 mm) and QuickDASH (0-100) scores (Disability of the Arm, Shoulder and Hand) for functionality.
JBJS Essent Surg Tech
August 2025
Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Background: Achieving adequate exposure can be difficult in cases of revision total hip arthroplasty (THA). Splitting the gluteus maximus muscle with use of a Kocher-Langenbeck approach is the most common technique when performing a posterior approach to the hip. However, superior exposure of the ilium is limited by the superior gluteal neurovascular bundle (SGB).
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