Synthesis of 2-Indolyl -Glycoside Neopetrosins A and C and Congeners via Ni-Catalyzed Photoreductive Cross-Coupling.

Org Lett

State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

Published: September 2023


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Article Abstract

The synthesis of neopetrosins A and C, two 2-indolyl -α-d-mannopyranosides, and their congeners has been realized via a direct Ni/photoredox-catalyzed reductive coupling of 3-methoxycarbonyl-2-iodo-1-indoles with pyranosyl bromides.

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http://dx.doi.org/10.1021/acs.orglett.3c02601DOI Listing

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