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Background: The aim of this study is to evaluate the added value of early bone single photon emission computed tomography (SPECT) by comparison to pseudoplanar imaging.
Methods: Fifty patients were retrospectively included from 3 centers. Reading sessions were organized using: late-phase acquisition alone; early SPECT and late-phase acquisition; early pseudoplanar and late-phase acquisition. The comparison between early SPECT and MIP was performed using a McNemar Test. Patients for whom early SPECT had provided additional information were also compared with patients for whom early SPECT had not.
Results: Fifty patients were included. Early SPECT was superior to pseudoplanar MIP in 10/50 patients (20.0%, P=0.044). No significant difference was found between this group and the remainder. Early SPECT changed the diagnosis established from late-phase imaging in 21/50 patients.
Conclusions: Early SPECT is a promising tool in bone imaging and change the diagnosis in one fifth of the cases by comparison to pseudoplanar imaging.
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http://dx.doi.org/10.23736/S1824-4785.23.03523-9 | DOI Listing |
Schizophr Res
September 2025
UHC Sestre Milosrdnice, Department of Psychiatry, Zagreb, Croatia; Catholic University of Croatia, School of Medicine, Zagreb, Croatia.
Objective: Thalamic abnormalities have been associated with clinical and cognitive symptoms of schizophrenia, yet their role in the early stages of the disorder remain unclear. This study aimed to examine and compare thalamic perfusion differences between first-episode schizophrenia (FES) and early-course schizophrenia (ECS), along with their associations with cognitive performance and symptom severity.
Methods: This study included 100 unmedicated schizophrenia patients aged 19-30: 50 FES and 50 ECS (<5 years, ≥2 episodes).
J Electrocardiol
August 2025
Department of Cardiology, Kırşehir Ahi Evran Training and Research Hospital, Kırşehir, Turkey. Electronic address:
Background: Ischemia with non-obstructive coronary arteries (INOCA) represents a diagnostic and therapeutic challenge, often related to coronary microvascular dysfunction (CMD). Identifying non-invasive electrocardiographic markers that predict ischemia in this population remains a clinical priority. P-wave peak time (PWPT), reflecting atrial conduction delay, has been linked to ischemic pathophysiology.
View Article and Find Full Text PDFJ Nucl Cardiol
July 2025
Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.
Systemic amyloidosis is a complex disorder, making early and accurate diagnosis challenging. The most common types are associated with misfolded transthyretin or immunoglobulin light chains, where cardiac and renal amyloidosis portend the worst prognosis. Peptide p5+14 can bind all types of amyloid via multivalent electrostatic interactions.
View Article and Find Full Text PDFCurr Hypertens Rev
August 2025
Department of Radiology, School of Medicine, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Introduction: Left Ventricular Dysfunction (LVD) is a frequent complication in Diabetes mellitus (DM) patients, often worsened by cardiovascular disease. This study explores the role of dipyridamole (DP)-induced heart rate variability and G-SPECT imaging in evaluating LVD in DM patients.
Aim: This study aimed to evaluate the relationship between heart rate ratio (HRR) during DP stress and LVD parameters derived from gated SPECT (G-SPECT) in DM patients, aiming to identify if HRR can serve as a marker for early LVD assessment.
Intractable Rare Dis Res
August 2025
Department of Radiology & Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
Renal oncocytomas are benign renal tumours characterized by a central stellate scar that are indistinguishable on CT/MR imaging from malignant chromophobe renal cell carcinomas (ChrRCCs). Renal oncocytomas and ChrRCCs can be separate entities but can also co-exist on a spectrum in hybrid oncocytic/ chromophobe tumours. In the past, invasive biopsy and pathologic diagnosis has been relied on to differentiate these lesion and direct management.
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