98%
921
2 minutes
20
Background: As outpatient chemotherapy treatment increases, cancer patients receiving chemotherapy spend more time at home. In addition, since the types of chemotherapy are gradually expanding, it will be essential to prepare patient self-management strategies for various chemotherapy-related side effects. This study aimed to develop a platform (called Smart Cancer Care) to implement a chemotherapy side effect management program and to evaluate its feasibility.
Methods: Smart Cancer Care comprises an application for patients and a dashboard for medical staff. Thirty-two symptoms to be managed using Smart Cancer Care were summarized through a literature review and Delphi. Management guidelines were developed based on the severity of each symptom (3 stages), and installed in Smart Cancer Care according to the Common Terminology Criteria for Adverse Events (CTCAE) v5.0 guidelines. To evaluate the feasibility of the developed application and medical dashboard, cancer patients and cancer treatment medical staff used Smart Cancer Care for 2 to 3 weeks and subsequently reported the experience of using them.
Results: The patient application provided a list of symptoms according to the cancer type and anticancer drug enabling presence and severity of each symptom to be evaluated. Patients received management guidelines for symptoms based on the symptom evaluation results. On the medical staff dashboard, administrators and authorized medical personnel could access and assess information regarding side effects and symptom severity submitted by the patient. The feasibility and usefulness of Smart Cancer Care were confirmed through a pilot test targeting 30 patients and 24 chemotherapy-related medical staff. For patients, the evaluation score for the "The program will be helpful when seeing medical staff" item was the highest. For medical staff, the score for the "By checking the patient's symptoms using the program, it helps to take appropriate measures for the patient" item was the highest. Although minor corrections were raised, most patients and medical staff expected that Smart Cancer Care would help their treatment.
Conclusions: The configuration of the application and dashboard of Smart Cancer Care detailed in this study could be used for the development of a widely accepted platform to implement a chemotherapy side effect management program.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10466749 | PMC |
http://dx.doi.org/10.1186/s12913-023-09871-0 | DOI Listing |
Carbohydr Polym
November 2025
College of Smart Agriculture (Research Institute), Xinjiang University, Urumqi 830017, China. Electronic address:
Oligosaccharides are increasingly valuable for preparing noble metal (NM) nanoparticles (NPs) due to excellent biocompatibility and abundant reducing functional groups (e.g., hydroxyl, amino, and aldehyde groups).
View Article and Find Full Text PDFComput Biol Chem
September 2025
School of Information Engineering, Nanchang Institute of Technology Nanchang, Jiangxi 330099, PR China; Jiangxi Province Key Laboratory of Smart Water Conservancy, Nanchang Institute of Technology, Nanchang, Jiangxi, PR China. Electronic address:
Cancer presents a significant challenge in the field of public health due to its high incidence, mortality rate, and inherent heterogeneity. Integrating multi-omics biological data offers a comprehensive and intricate understanding of biological processes, disease mechanisms, and cancer subtyping, rendering it an influential tool for scientific research. Nevertheless, current approaches to integrating multi-omics data often fail to consider the scale of data in feature information and overlook the analysis of the individual and shared feature expressions in multi-omics data.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
State Key Laboratory for Quality and Safety of Agro-Products, Institute of Plant Virology, Ningbo University, Ningbo, 315211, China.
Drug delivery based on dynamic morphological transformation represents the cutting-edge strategy at the forefront of chemotherapy, integrating individual advantages that depend on the delivery stage and spatially resolved morphology. However, developing a tumor-specific, in vivo morphologically transformable small-molecule drug delivery system to achieve enhanced drug accumulation and photodynamic therapy (PDT) efficacy remains challenging. In this study, a multifunctional PDT formulation using natural small molecules as nanocarriers is developed, combining a tumor-targeting photosensitizer and anti-angiogenic therapy.
View Article and Find Full Text PDFMed Oncol
September 2025
Chemistry Department, Faculty of Science, Cairo University, Cairo, Egypt.
Pancreatic cancer is among the most lethal forms of cancer, with a five-year survival rate under 7%, primarily due to its late clinical presentation and rapid disease progression. Although the oncogenic development of pancreatic tumors can span over a decade, early diagnosis remains a major clinical challenge, as current diagnostic approaches-including imaging modalities and blood-based markers like CA19-9-lack the requisite sensitivity for detecting early-stage disease. Liquid biopsy has emerged as a promising, non-invasive diagnostic technique by enabling the detection of circulating tumor-specific nucleic acids, particularly circulating tumor DNA (ctDNA) and microRNAs (miRNAs).
View Article and Find Full Text PDFACS Appl Bio Mater
September 2025
School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China.
Multidrug resistance (MDR) is a significant factor contributing to chemotherapy failure in the clinical treatment of nonsmall cell lung cancer (NSCLC). The combination of P-glycoprotein (P-gp) inhibitors with chemotherapeutic agents can effectively overcome MDR by inhibiting drug efflux from NSCLC cells. However, achieving a satisfactory therapeutic effect through the codelivery of chemotherapeutic agents and P-gp inhibitors remains challenging due to their different pharmacokinetics and physicochemical properties.
View Article and Find Full Text PDF