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To achieve real-time blood pressure monitoring, a novel non-invasive method is proposed in this article. Electrocardiographic (ECG) and pulse wave signals (PPG) are fused from a multi-omics signal-level perspective. A physiological signal fusion matrix and fusion map, which can estimate the blood pressure of blood loss(BPBL), are constructed. The results demonstrate the efficacy of the fusion map model, with correlation values of 0.988 and 0.991 between the estimated BPBL and the true systolic blood pressure (SBP) and diastolic blood pressure (DBP), respectively. The root mean square errors for SBP and DBP were 3.21 mmHg and 3.00 mmHg, respectively. The model validation showed that the fusion map method is capable of simultaneous highlighting of the respective characteristics of ECG and PPG and their correlation, improving the utilization of the information and the accuracy of BPBL. This article validates that physiological signal fusion map can effectively improve the accuracy of BPBL estimation and provides a new perspective for the field of physiological information fusion.
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http://dx.doi.org/10.1016/j.medengphy.2023.104037 | DOI Listing |
Neurocrit Care
September 2025
Department of Clinical Sciences Lund, Neurosurgery, Department of Clinical Sciences, Lund University, Lund, Sweden.
Background: Many traumatic brain injury (TBI) treatment protocols, including the Lund concept, advocate the highest point of the subarachnoid space (typically the vertex) as the zero-reference point for intracranial pressure (ICP) and the level of the right atrium as the zero-reference point for mean arterial blood pressure (MAP). In 2017, at the Department of Neurosurgery in Lund, Sweden, the zero-reference points for ICP and MAP were both changed to the external auditory meatus (EAM), thus altering the calculated cerebral perfusion pressure (CPP) levels. We hypothesized that the ICP and MAP levels obtained from the different zero-reference points resulted in altered neurocritical care management and/or patient outcome.
View Article and Find Full Text PDFNeurocrit Care
September 2025
Department of Paediatrics, Cambridge University, Cambridge, UK.
Background: Low cerebral perfusion pressure (CPP) has previously been identified as a key prognostic marker after pediatric traumatic brain injury (TBI). Cerebrovascular autoregulation supports stabilization of cerebral blood flow within the autoregulation range. Beyond the upper limit of this range, cerebral blood flow increases with increasing CPP, leading to increased risk of intracranial hypertension and blood-brain barrier disruptions.
View Article and Find Full Text PDFJ Gen Intern Med
September 2025
Department of Family Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR, USA.
Background: Hypertension is the most prevalent reversible risk for cardiovascular morbidity and mortality. Blood pressure (BP) control is poor nationally and varies by race/ethnicity, and there is minimal understanding of the impact of country of origin.
Objective: To examine racial/ethnic disparities in BP control among high-risk patients and among Latino patients disaggregated by country of origin.
Clin Exp Nephrol
September 2025
Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Background: Sacubitril/valsartan is typically prescribed for patients with heart failure and hypertension. We previously reported that sacubitril/valsartan provides comparable blood pressure (BP) reduction and superior tolerability compared to thiazide diuretics. This post hoc study aimed to compare the effects of sacubitril/valsartan and thiazide diuretics in patients with chronic kidney disease (CKD).
View Article and Find Full Text PDFIntensive Care Med Exp
September 2025
Critical Care Division, Integrated Hospital Care Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Background: The relationship between carbon dioxide pressures (PCO) and contents (CCO) is linked to the Haldane effect. Nevertheless, under shock conditions, hydrogen ion accumulation might strongly influence the discrepancies between PCO and CCO. This study aims to evaluate the impact of hydrogen ion accumulation and hemoglobin oxygen saturation (Haldane effect) on PCO:CCO relationships during induction and resuscitation of endotoxemic shock.
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