98%
921
2 minutes
20
Background And Aims: Primary percutaneous coronary intervention (PCI) is regarded as the most preferred strategy in ST-segment elevation myocardial infarction (STEMI). Thrombolysis in Myocardial Infarction (TIMI) flow grade has been an important and cohesive predictor of outcomes in STEMI patients. We sought to evaluate potential variables associated with the risk of suboptimal TIMI flow after PCI in patients with anterior wall STEMI.
Methods: We evaluated 107 patients admitted to our hospital between 1 January 2019 and 31 December 2021 with a diagnosis of anterior wall STEMI treated with primary PCI.
Results: Suboptimal TIMI flow grade (≤2) after PCI occurred in 14 (13%) patients while grade 3 was found in 93 (87%) of them presenting with anterior wall STEMI. Failure to achieve optimal TIMI 3 flow grade after PCI was associated with lower TIMI grade prior to PCI (OR 0.5477, 95% CI 0.2589-0.9324, = 0.02), greater troponin concentration before (OR 1.0001, 95% CI 1-1.0001, = 0.0028) and after PCI (OR 1.0001, 95% CI 1-1.0001, = 0.0452) as well as lower mean minimal systolic blood pressure (OR 0.9653, 95% CI 0.9271-0.9985, = 0.04).
Conclusions: Among predictors of suboptimal TIMI flow grade after PCI, we noted lower TIMI grade flow pre-PCI, greater serum troponin concentrations in the periprocedural period and lower mean minimal systolic blood pressure.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10455189 | PMC |
http://dx.doi.org/10.3390/jpm13081217 | DOI Listing |
Cardiol J
September 2025
Department Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Education Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Background: The aim of this study was to investigate whether serum uric acid to serum creatinine ratio (SUA/SCr) predicts the early major adverse cardiovascular and cerebrovascular events (MACCEs) in patients with ST elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVCAD).
Methods: This study was designed retrospectively and included 572 patients with a mean age of 61.9 ± 12.
JACC Adv
August 2025
Hennepin Healthcare, Department of Emergency Medicine and University of Minnesota, Minneapolis, MN, USA.
Background: Despite no objective definition, hyperacute T waves (HATW) are recommended by the American College of Cardiology as a STEMI equivalent finding, requiring emergent reperfusion.
Objective: We sought to derive and validate a quantitative definition of HATW.
Methods: We retrospectively evaluated adults with possible ACS across five PCI centers.
Acta Cardiol
September 2025
Bakırköy Dr. Sadi Konuk Training and Research Hospital, Bakırköy, İstanbul, Turkey.
Background: TIMI (Thrombolysis In Myocardial Infarction) frame count is a quantitative method that objectively assesses slow coronary blood flow. In our study, corrected TIMI frame count and non-invasive parameters such as Tp-e interval and Tp-e/QT ratio were investigated after revascularization in patients with ST Elevation Myocardial Infarction (STEMI).
Methods: Patients who were admitted to our hospital with a preliminary diagnosis of STEMI between January 2020 and July 2020 were included in our study.
J Cardiovasc Dev Dis
August 2025
Department of Biochemistry, Medical University, 1431 Sofia, Bulgaria.
(1) Introduction: Distal coronary emboli occur in up to 15-30.5% of patients undergoing percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) and are associated with poor myocardial reperfusion in the territory of the infarct-related artery. The objective of this study was to analyze the possible laboratory, clinical and imaging indicators of distal coronary embolism detected with an angiography at the time of PCI with stent implantation for acute coronary syndrome (ACS).
View Article and Find Full Text PDFCureus
July 2025
Internal Medicine, Fairfield General Hospital - Northern Care Alliance NHS Foundation Trust, Manchester, GBR.
Percutaneous coronary intervention (PCI) is a minimally invasive procedure that plays an important role in relieving an occlusion of the coronary arteries, allowing blood circulation to the cardiac tissues. It is central to the management of coronary heart disease. In recent years, there has been an increase in the use of PCI across the African continent, and this review aims to evaluate and report the clinical outcomes of PCI use in Africa among patients with coronary heart disease.
View Article and Find Full Text PDF