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Background: Computed tomography (CT) of the brain is associated with radiation exposure to the lens of the eyes. Therefore, it is necessary to optimize scan settings to keep radiation exposure as low as reasonably achievable without compromising diagnostic image information. The aim of this study was to compare the effectiveness of the five practical techniques for lowering eye radiation exposure and their effects on diagnostic image quality in pediatric brain CT.
Methods: The following scan protocols were performed: reference scan, 0.06-mm Pbeq bismuth shield, 30% globally lowering tube current (GLTC), reducing tube voltage (RTV) from 120 to 90 kVp, gantry tilting, and combination of gantry tilting with bismuth shielding. Radiation measurements were performed using thermoluminescence dosimeters. Objective and subjective image quality was evaluated.
Results: All strategies significantly reduced eye dose, and increased the posterior fossa artifact index and the temporal lobe artifact index, relative to the reference scan. GLTC and RTV increased image noise, leading to a decrease signal-to-noise ratio and contrast-to-noise ratio. Except for bismuth shielding, subjective image quality was relatively the same as the reference scan.
Conclusions: Gantry tilting may be the most effective method for reducing eye radiation exposure in pediatric brain CT. When the scanner does not support gantry tilting, GLTC might be an alternative.
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http://dx.doi.org/10.4103/jmss.jmss_19_22 | DOI Listing |
Photosynth Res
September 2025
College of Life Sciences, Shanghai Normal University, Shanghai, 200235, China.
Euglena sanguinea (Ehrenberg 1831) is one of the earliest reported species within the genus Euglena. Its prolific proliferation leading to red algal bloom has garnered significant scientific attention due to its ecological and environmental impacts. Despite this, research on E.
View Article and Find Full Text PDFInterv Neuroradiol
September 2025
University Clinic for Neuroradiology, University Hospital Magdeburg, Magdeburg, Germany.
BackgroundAt present, nonvirtual neurovascular training can be performed using either an angiographic suite under fluoroscopic guidance (entailing radiation exposure) or direct optical visualization with a camera-based system. The angiographic approach offers high-fidelity visualization and catheter control but is constrained by the limited availability of such specialized facilities, whereas the camera-based approach can be implemented virtually anywhere yet lacks comparable realism in key procedural aspects. The objective of this work is to develop and evaluate a novel camera-based angiography training system (CBATS) that generates artificial angiograms and roadmaps, thereby combining the advantages of both imaging techniques while eliminating radiation exposure.
View Article and Find Full Text PDFDrug Dev Res
September 2025
R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, India.
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, with "epidermal growth factor receptor (EGFR)" mutations playing a pivotal role in tumor progression and carcinogenesis. "Third-generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs)," such as Osimertinib, have significantly improved treatment outcomes by overcoming resistance mechanisms like the T790M mutation. However, Osimertinib's clinical application is limited by cardiotoxicity concerns, necessitating safer alternatives.
View Article and Find Full Text PDFJ Geriatr Cardiol
August 2025
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel Disease, Beijing Key Laboratory of Precision Medicine of Coronary Atherosclerotic Disease, Clinical Center for Coronary Heart Disease, Capital Medical University, Beijing,
Objective: To evaluate the safety and effectiveness of robot-assisted percutaneous coronary intervention (R-PCI) compared to traditional manual percutaneous coronary intervention (M-PCI).
Methods: This prospective, multicenter, randomized controlled, non-inferior clinical trial enrolled patients with coronary heart disease who met the inclusion criteria and had indications for elective percutaneous coronary intervention. Participants were randomly assigned to either the R-PCI group or the M-PCI group.
Rep Pract Oncol Radiother
August 2025
Department of Electroradiology, Poznan University of Medical Sciences, Poznan, Poland.
Background: To compare doses deposited to the liver during right breast radiotherapy with static and dynamic radiotherapy techniques. The second aim was to introduce the liver load index (LLI), a novel index developed to estimate radiation exposure to the liver prior to treatment selection.
Materials And Methods: We prepared radiotherapy treatment plans for ten patients with right breast cancer.