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Article Synopsis
- - Cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC) are significant types of liver cancer that impact the immune response due to the role of T regulatory (Treg) cells in suppressing antitumor immunity.
- - A study was conducted on healthy individuals, CCA patients, and HCC patients to assess changes in natural killer (NK) cells and T cell subsets before and after surgical tumor removal, using various blood assays.
- - Findings revealed that both types of cancer patients exhibited alterations in Treg cell populations before surgery, with an increase in certain Treg cells after tumor resection, indicating potential mechanisms of immune modulation following surgery.