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Article Abstract
In this new series reviewing recent developments in market access, we highlight publications investigating health technology assessment (HTA) guidance, review processes and outcomes across the world and discuss how forthcoming changes in the HTA and regulatory environment in the European Union may allow for more consistency in decision making.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10690433 | PMC |
| http://dx.doi.org/10.57264/cer-2023-0129 | DOI Listing |
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Purpose: In Armenia, a lower-middle-income country, cancer causes 21% of all deaths, with over half of cases diagnosed at advanced stages. Without universal health insurance, patients rely on out-of-pocket payments or black-market channels for costly immunotherapies, underscoring the need for real-world data to inform equitable policy reforms.
Methods: We conducted a multicenter, retrospective cohort study of patients who received at least one dose of an immune checkpoint inhibitor (ICI) between January 2017 and December 2023 across six Armenian oncology centers.
How data assets influence enterprise persistent innovation: Evidence from China.
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View Article and Find Full Text PDFCohort profile: The Multiethnic Lifestyle, Obesity and Diabetes Registry in Malaysia (MeLODY) retrospective cohort in a middle-income country in Southeast Asia.
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View Article and Find Full Text PDFMolecular engineering for bitterness masking of natural products: from decoding structure-taste relationships to structure-driven bitterness suppression.
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Natural products have emerged as a vital source of active ingredients in medicine, food, and cosmetics due to their unique biological activities, safety profiles, and sustainability. However, most bioactive compounds in natural products are intensely bitter, limiting their use in pharmaceuticals and foods. The bitter taste attributes vary markedly among different compound classes, predominantly due to their structural characteristics.
View Article and Find Full Text PDFDetermining the power of a 1-sided z-test given only the power of the corresponding 2-sided test.
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Department of Psychology and Human Development, Vanderbilt University, 230 Appleton Place, Nashville, TN, 37203‑5721, USA.
Estimating statistical power is essential for designing behavioral medicine studies efficiently and conserving finite resources. Sometimes behavioral medicine researchers are interested in calculating power for 1-sided z-tests of individual parameters (e.g.
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