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| http://dx.doi.org/10.1016/j.brs.2023.08.004 | DOI Listing |
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Effectiveness of high-frequency repetitive transcranial magnetic stimulation coupled with rehabilitation in patients with spinal cord injury: a systematic review.
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Department of Physiology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
Background: Spinal Cord Injury (SCI) leads to partial or complete sensorimotor loss because of the spinal lesions caused either by trauma or any pathological conditions. Rehabilitation, one of the therapeutic methods, is considered to be a significant part of therapy supporting patients with spinal cord injury. Newer methods are being incorporated, such as repetitive Transcranial Magnetic Stimulation (rTMS), a Non-Invasive Brain Stimulation (NIBS) technique to induce changes in the residual neuronal pathways, facilitating cortical excitability and neuroplasticity.
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Danish Research Centre for Magnetic Resonance, Department of Radiology and Nuclear Medicine, Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark, Kettegård Allé 30, 2650 Hvidovre, Denmark; Institute of Neuroscience, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N,
Background: We recently demonstrated that single-pulse TMS of the primary sensorimotor hand area (SM1) elicits an immediate transcranial evoked potential (iTEP). This iTEP response appears within 2-8 ms post-TMS, featuring high-frequency peaks superimposed on a slow positive wave. Here, we used a linear TMS-EEG mapping approach to characterize the rostro-caudal iTEP expression and compared it to that of motor-evoked potentials (MEPs).
View Article and Find Full Text PDFEffect of high-frequency rTMS on cognitive deficits in schizophrenia: A randomized, double blind, sham-controlled trial.
Indian J Psychiatry
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Department of Psychiatry, Serenity Clinic, New Delhi, India.
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Divergent responses of glutamatergic and GABAergic prefrontal neurons underlie changes in excitability following low and high frequency repetitive brain stimulation.
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Research Service, VA San Diego Healthcare System, La Jolla, CA, 92161, USA; NEATLabs, Department of Psychiatry, UC San Diego, La Jolla, CA, 92093, USA; Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, CA, 92161, USA; Mental Health Care Line, VA San Diego H
Background: Repetitive brain stimulation is hypothesized to bidirectionally modulate excitability, with low-frequency trains decreasing and high-frequency (>5 Hz) trains increasing excitability in the brain. However, most insights on the neuroplastic effects of repetitive stimulation protocols stem from non-invasive human studies (TMS/EEG) or from rodent slice physiology. Here, we developed a rodent experimental preparation enabling imaging of cellular activity during repetitive stimulation protocols in vivo to understand the mechanisms by which brain stimulation modulates excitability of prefrontal cortical neurons.
View Article and Find Full Text PDFEffects of repetitive transcranial magnetic stimulation over the supplementary motor area on balance and postural control in stroke patients: a randomized controlled trial.
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September 2025
Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China.
Objective: To investigate the effects of 10 Hz repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) on balance and postural control in patients with stroke.
Methods: In this randomized controlled trial, 40 patients withbalance disorders were randomly assigned to either the transcranial magneticstimulation (TMS) group ( = 20) or the sham group ( = 20). Both groups underwent a two-week standardized physical therapy.