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We have previously published a novel transfusion medicine curriculum for first-year anesthesiology residents, making available open access learning materials. We now present a curriculum iteration, by incorporating resident feedback and developing an additional "capstone" session for use at the end of the rotation that integrates several learning points into a practical problem-based simulation. This iteration of the curriculum was piloted with the 2019-2020 PGY-1 anesthesiology residents of the University of Wisconsin Hospitals and Clinics. Pre-course and post-course surveys, which assessed trainee understanding of course topics, were used to subjectively evaluate the usefulness of the curriculum. Results of the surveys demonstrated post-test mean scores were significantly increased when compared with the equivalent pre-course questions. This suggests the piloted curriculum iteration serves as a useful tool for resident learning. As an adjunct to our previous existing materials, in the spirit of open-access education, we share this additional curriculum material, consisting of four patient cases with 16 questions that can be used immediately for teaching purposes.
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http://dx.doi.org/10.1016/j.acpath.2023.100089 | DOI Listing |
PLoS One
September 2025
Department of Clinical Nursing Teaching and Research Section, School of Nursing, Hebei Medical University, Shijiazhuang, China.
Background And Aims: While perceived stress and coping strategies have been established as significant determinants of quality of life (QoL) in patients with solid malignancies, their impact on hematological malignancy population have not been fully elucidated. This study aimed to examine how perceived stress and medical coping strategies interact with sociodemographic factors to influence QoL in patients with hematologic malignancies.
Methods: The study, involving 185 hematologic cancer patients in China, was conducted between August 2024 and December 2024.
Eur J Neurosci
September 2025
Department of Anesthesiology and Pain Medicine, University of California Davis, Davis, California, USA.
Voltage-gated K channels of the Kv2 family coassemble with electrically silent KvS subunits in specific subpopulations of brain neurons, forming heteromeric Kv2/KvS channels with distinct functional properties. Little is known about the composition and function of Kv2 channels in spinal cord neurons, however. Here, we show that while Kv2.
View Article and Find Full Text PDFDepress Anxiety
September 2025
Department of Anesthesiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan, China.
Aging is an inevitable process. Chronic pain and late-life depression frequently coexist in older adults. This study was aimed to explore the association between chronic pain and late-life depression in Chinese centenarians and oldest-old adults.
View Article and Find Full Text PDFImmunopharmacol Immunotoxicol
September 2025
Neuroscience Research Center, Suleyman Demirel University, Isparta, Türkiye.
Background: Microglia are brain resident cells that control neural network maintenance, damage healing, and brain development. Microglia undergo apoptosis, cytokine production, and reactive free radicals of oxygen (ROS) in response to lipopolysaccharide (LPS) stimulation. TRPM2 is activated by LPS-induced oxidative stress, but it is inhibited by carvacrol (CARV) and N-(p-amylcinnamoyl)anthranilic acid (ACA).
View Article and Find Full Text PDFAppl Clin Inform
August 2025
Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
Clinical decision support (CDS) tools in electronic health records (EHRs) often face low uptake due to limited usability, workflow integration, and other implementation issues. We recently designed and implemented the STRATIFY-CDS tool, which calculates a validated risk-prediction model and recommends disposition for emergency department (ED) patients with acute heart failure. Despite applying human-centered design and implementation science strategies, initial utilization in the first 3 months of the STRATIFY-CDS tool was just 3%.
View Article and Find Full Text PDF