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This article presents a low-noise high-power-efficiency analog front-end (AFE) for capacitive-micromachined-ultrasonic transducers (CMUT). Implemented in 28-nm CMOS technology, the proposed AFE features three-stage continuous time-gain compensation (TGC) embedded in both trans-impedance amplifiers (TIAs) and an analog beamformer to provide a large compensation range with no extra power-consumption cost. The use of noise cancellation and capacitive feedback optimizes the noise performance of TIAs. The first stage of the TGC is built in the TIA by adjusting the positive and negative resistance loads, which are composed of voltage-controlled transistor arrays. An all-pass passive network is used as the delay unit of the analog beamformer, meanwhile achieving the second TGC stage. Phase shift for all frequency components in the ultrasound pass-band is manifested as a delay to the echoes. The third stage of the TGC is merged with a summing unit, which is a closed-loop amplifier with variable resistance feedback. The design takes into account the ability to handle large signals and power consumption, with TIA and beamforming operating at voltages of 2.5 V and 0.9 V, respectively. Experimental results show that the proposed AFE achieves a 2.11 pA/√Hz input-referred noise (IRN) at the 5 MHz center frequency of the echoes while consuming only 1.02 mW/channel. A total exponential TGC range of 60 dB with continuous ranges of 12 dB, 24 dB, and 24 dB assigned to three stages has been verified for this work.
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http://dx.doi.org/10.1109/TBCAS.2023.3302648 | DOI Listing |
J Environ Manage
December 2024
School of Geography and Ocean Science, Nanjing University, Nanjing, 210023, Jiangsu, China.
The relationship between carbon sources and sinks, along with their balance, is a crucial indicator for assessing ecosystem health. Ecosystem protection mitigates climate change and promotes the carbon cycle balance. Consequently, to effectively assess the status of carbon sources and sinks in an oasis ecosystem, this study utilized remote sensing and statistical data to estimate the natural carbon sources and sinks, energy carbon emissions(ECE), and carbon surpluses or deficits in the urban agglomeration of the northern slopes of the Tianshan Mountains(UANSTM) for a period 2000-2022 from a perspective of the natural-social-economic system.
View Article and Find Full Text PDFPLoS One
October 2024
Northwestern-Argonne Institute for Science and Engineering, Evanston, IL, United States of America.
Over the last four years, each successive wave of the COVID-19 pandemic has been caused by variants with mutations that improve the transmissibility of the virus. Despite this, we still lack tools for predicting clinically important features of the virus. In this study, we show that it is possible to predict the PCR cycle threshold (Ct) values from clinical detection assays using sequence data.
View Article and Find Full Text PDFCarbohydr Polym
March 2024
Department of Orthopedics Trauma and Microsurgery, Zhongnan Hospital, Wuhan University, Wuhan, 430071, PR China. Electronic address:
The migration of fibroblasts and endothelial cells is a critical determinant of wound-healing outcomes for skin injuries. Here, hyaluronic acid-tyramine (HAT) and thiolated glycol chitosan (TGC) conjugates were combined with copper-doped bioglass (ACuBG) nanoparticles to build a novel type of multi-crosslinked hydrogel for stimulating the migration of cells, and thus, expediting wound healing. The optimally devised HAT/TGC/ACuBG gels had markedly improved strength and stiffness compared to the gels built from either HAT or TGC while showing sufficient elasticity, which contributes to stimulating the migration of fibroblasts.
View Article and Find Full Text PDFInfect Drug Resist
August 2023
Department of Gastroenterology, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.
Objective: Infection is a common complication of acute pancreatitis (AP). (KP) is one of the most common pathogens associated with nosocomial infections. Our study focuses on investigating the clinical characteristics and risk factors for death of infections in AP patients, further to quantify the prognosis of the patients, and provide evidence for guiding antibiotic use and improving prognosis.
View Article and Find Full Text PDFIEEE Trans Biomed Circuits Syst
October 2023
This article presents a low-noise high-power-efficiency analog front-end (AFE) for capacitive-micromachined-ultrasonic transducers (CMUT). Implemented in 28-nm CMOS technology, the proposed AFE features three-stage continuous time-gain compensation (TGC) embedded in both trans-impedance amplifiers (TIAs) and an analog beamformer to provide a large compensation range with no extra power-consumption cost. The use of noise cancellation and capacitive feedback optimizes the noise performance of TIAs.
View Article and Find Full Text PDF