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Aggressive SM + AML has limited therapeutic options. Even a strong combination of decitabine-venetoclax-midostaurin has a transient effect on AML and a mitigated effect on SM. Larger series are required to identify the best therapeutic strategy.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352544 | PMC |
http://dx.doi.org/10.1002/ccr3.7134 | DOI Listing |
Am J Ophthalmol
September 2025
Department of Ophthalmology, Université de Montréal, Montréal, Québec, Canada.
Purpose: To evaluate the incidence, risk factors, management strategies, and visual outcomes of retinal detachment (RD) following Boston Keratoprosthesis Type 1 (KPro) implantation.
Design: Single-center, retrospective observational case series.
Methods: Medical records of 157 eyes from 122 adult patients who underwent Boston Type 1 KPro implantation at a tertiary care center between 2008 and 2022 were reviewed.
Asian J Psychiatr
September 2025
Department of Psychiatry and Mental Health, Faculty of Medicine, Universidad de Chile, Santiago, Chile; Translational Psychiatry Laboratory (Psiquislab), Faculty of Medicine, Universidad de Chile, Santiago, Chile; Millennium Nucleus to Improve the Mental Health of Adolescents and Youths (IMHAY), San
Background: Schizophrenia spectrum disorders often emerge in adolescence or early adulthood and are a leading cause of global disability. Early identification of clinical high‑risk for psychosis (CHR‑P) can reduce comorbidity and shorten untreated psychosis duration, yet clinician‑administered tools (e.g.
View Article and Find Full Text PDFJ Clin Ultrasound
September 2025
Hebei General Hospital, Shijiazhuang, China.
Background: Acute ischemic stroke (AIS) is characterized by high incidence, sudden onset, and often poor prognosis. Carotid atherosclerosis plays a crucial role in its pathogenesis, and ultrasound imaging offers a non-invasive method for evaluating carotid plaque characteristics. This study aimed to develop and validate a prediction model for AIS risk based on a novel ultrasound-based carotid plaque scoring system combined with clinical risk factors.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
October 2025
Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
Physiotherapy
June 2025
PenCRU (Peninsula Childhood Disability Research Unit), Department of Health & Community Sciences, University of Exeter Medical School, University of Exeter, St Luke's Campus EX1 2LU, UK. Electronic address:
Objectives: Children and young people with complex neurodisability (CYPCN) are at high risk of respiratory illness, frequent hospital admissions and premature death. This study aimed to test the acceptability and feasibility of Breathe-Easy, a novel night-time postural intervention to improve respiratory health in CYPCN.
Design: Case series design incorporating a pre-post interventional study and qualitative study.