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Background: Urinary incontinence is a urinary disorder in which urine leaks out involuntarily. This disorder seriously affects the quality of life of patients. For patients with mild incontinence, conservative treatment and medication may be the ideal treatment modality, but for patients with severe incontinence, an artificial urinary sphincter is currently a better treatment option.
Methods: In order to design an ideal artificial urinary sphincter, this article first searched and collected literature based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses searched strategy by selecting specific subject terms and reviewed the artificial urinary sphincters that are currently in the research stage based on different activation methods.
Results: In response to the deficiencies of the existing artificial urinary sphincter, this article discusses the future optimization of the artificial urinary sphincter from three aspects: individual improvement of the artificial urinary sphincter, engineering design elements, and optimization of the artificial urinary sphincter manufacturing process.
Conclusions: The manufacture of an idealized artificial urinary sphincter capable of meeting clinical needs is of great importance to improve the quality of life of patients. However, this approach is a reasonable option to explore and should not be overestimated until further evidence is available.
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http://dx.doi.org/10.1111/aor.14606 | DOI Listing |
Clin Infect Dis
September 2025
VA Maryland Health Care System, Baltimore, Maryland, USA.
A retrospective cohort study compared generative artificial intelligence (GenAI) vs. infection control expert for catheter-associated urinary tract infection (CAUTI) detection. Sensitivity was 95.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
Department of Biomedical Engineering, University of Houston, Houston, TX, 77204, USA.
Neurogenic bladder and lower urinary tract (LUT) dysfunctions encompass a wide variety of urinary disorders resulting from nervous system impairments. Unfortunately, conventional treatments are still limited and can have significant complication rates, especially when stent implantations or other surgical procedures are involved. Therefore, there is a critical need to develop novel therapeutic strategies and pharmacological approaches to address these challenging urological conditions.
View Article and Find Full Text PDFMol Biol Rep
September 2025
Department of Physiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
Aim: Ischemia-reperfusion (IR) injury-induced renal failure is a major cause of death and morbidity. Unfortunately, there is currently no proven protective therapy. The aim of the study is to investigate the protective effect of D-carvone against the renal ischemia-reperfusion (RIR) injury.
View Article and Find Full Text PDFNeurourol Urodyn
September 2025
Department of Urology, School of Medicine, Division of Pediatric Urology, Marmara University, Istanbul, Turkey.
Aim: Uroflowmetry (UF) is one of the most commonly used noninvasive tests in the evaluation of children with lower urinary tract symptoms (LUTS). However, studies have highlighted a weak agreement among experts interpreting voiding patterns. This study aims to assess the impact of Machine Learning (ML) models, which have become increasingly prevalent in medicine, on the interpretation of voiding patterns.
View Article and Find Full Text PDFBiosens Bioelectron
August 2025
Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine Vision and Brain Health), Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang, 325000, China; Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, 1
The escalating threat of antimicrobial resistance is exacerbated by delayed diagnostics and improper antibiotics use, underscoring an urgent demand for rapid, versatile AST tools to support evidence-based prescribing. In this study, we present an innovative, generalizable phenotypic AST approach by quantifying bacterial gDNA copy number variations (CNVs) following 0.5-h-brief culturing with antibiotic exposure, termed spatially encapsulated emulsions (SEE)-phAST.
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