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Objective: Our team designed a long-lasting, well-sealed microphone, which uses laser welding and vacuum packaging technology. This study examined the sensitivity and effectiveness of this new floating piezoelectric microphone (NFPM) designed for totally implantable cochlear implants (TICIs) in animal experiments and intraoperative testing.
Methods: Different NFPM frequency responses from 0.25 to 10 kHz at 90 dB SPL were analyzed using in vivo testing of cats and human patients. The NFPM was tested in different positions that were clamped to the ossicular chains or placed in the tympanic cavity of cats and human patients. Two volunteers' long incus foot and four cats' malleus neck of the ossicular chain were clamped with the NSFM. The output electrical signals from different locations were recorded, analyzed, and compared. The NFPM was removed after the test without causing any damage to the middle-ear structure of the cats. Intraoperative tests of the NFPM were performed during the cochlear implant surgery and the cochlear implant surgery was completed after all tests.
Results: Compared with the results in the tympanic cavity, the NFPM could detect the vibration from the ossicular chain more sensitively in cat experiments and intraoperative testing. We also found that the signal output level of the NFPM decreased as the acoustic stimulation strength decreased in the intraoperative testing.
Conclusion: The NFPM is effective in the intraoperative testing, making it feasible as an implantable middle-ear microphone for TICIs.
Level Of Evidence: 4 Laryngoscope, 134:937-944, 2024.
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http://dx.doi.org/10.1002/lary.30861 | DOI Listing |
Hear Res
August 2025
Department of Otolaryngology and Institute of Audioneurotechnology (VIANNA), Hannover Medical School, Hannover, Germany; Cluster of Excellence Hearing4all, Hannover, Germany.
Introduction: Direct piston-stimulation of the oval window with a middle ear implant, following a stapedotomy or stapedectomy, is one treatment option for patients with otosclerosis. Here, we experimentally investigated whether increasing the surface area of the actuated piston enhances transmission efficiency in oval window (OW) stimulation.
Methods: Fresh-frozen human cadaveric temporal bones (N = 14) were used to evaluate the output of different oval window couplers (OWCs) of A = 0.
Materials (Basel)
March 2025
College of Architecture and Civil Engineering, Beijing University of Technology, Beijing 100124, China.
With the rapid development of urban rail transit, the floating slab vibration isolation system has become widely used in the field due to its effective vibration reduction and isolation capabilities. Traditional floating slab vibration-isolation systems mainly focus on blocking vibration transmission, neglecting energy harvesting. This paper proposes a magnetic-coupled double-wing negative stiffness energy harvester for floating slabs.
View Article and Find Full Text PDFLangmuir
December 2024
Department of Chemical Engineering (BK21 FOUR Integrated Engineering Program), Kyung Hee University, Yongin 17104, South Korea.
This study presents a simple approach for fabricating low-density drug-polymer amorphous solid dispersions (ASDs) using a piezoelectric inkjet method, demonstrating potential applications for floating drug delivery systems (FDDS). By adjusting the ratio of two polymers, polylactic acid, and Eudragit RLPO, the floatability and drug release rate of the drug-polymer ASD particles can be easily manipulated. Kinetic model analyses have been conducted to interpret the drug release mechanism.
View Article and Find Full Text PDFInt J Biol Macromol
October 2024
The Library, Nanchang Normal University, Nanchang 330032, Jiangxi Province, PR China.
The conveniently recoverable piezocatalyst with self-floating and stable performance has drawn wide attention. Herein, MoS was anchored on 1-cm-square eucalyptus wood blocks via a facile hydrothermal/solvothermal process to fabricate two floating piezocatalysts, i.e.
View Article and Find Full Text PDFRev Sci Instrum
June 2023
School of Instrument Science and Opto-electronic Engineering, Hefei University of Technology, Hefei 230009, China.
To meet the high requirements for positioning accuracy and multiple dimensions of positioning systems in the fields of precision measurement and precision machining, a new submicron-precision three-dimensional (3D) low cross-interference positioning system is designed and fabricated in this paper. The 3D motion stage mainly includes a mechanical structure, a support and guide system, and a driving system. The Abbe offset error is eliminated by adopting a coplanar structure in the X and Y directions, thus minimizing the mutual cross-interference of the motion stage.
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