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http://dx.doi.org/10.1016/j.jcmg.2023.06.004 | DOI Listing |
Front Aging
August 2025
Department of Kinesiology, East Carolina University (ECU), Greenville, NC, United States.
Introduction: Declining functional capacity, both physical and cognitive, is a consequence of aging. However, exercise is a promising intervention to mitigate normal age- related decline. Although numerous studies have elucidated the benefits ofexercise per se, the effect of high-intensity interval training (HIIT) on a middle-aged population is less well-studied.
View Article and Find Full Text PDFBreast Cancer Res
September 2025
Department of Maternal, Child and Adolescent Health, School of Public Health, Ministery of Education Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Hefei, Anhui, China.
Background: The age of thelarche in girls has declined globally. While earlier menarche has been linked to higher breast density - a known risk factor for breast cancer - the association between earlier thelarche and breast density remains unclear.
Methods: 114 Girls presenting with idiopathic central precocious puberty without medication (ICPP), early thelarche (ET), and normal age at thelarche (NT) were recruited from pediatric endocrine clinics of three hospitals during the year of 2020-2021 in Hefei, Anhui Province, China and were followed up for 3-5 years.
Maturitas
August 2025
Reproductive Endocrinology Research Center, Research Institute for Endocrine Molecular Biology, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Foundation for Research and Education Excellence, Vestavia, AL, USA. Electronic address: fah.tehran
Background: Population studies elucidating the genetic architecture of early menopause have mainly focused on European ancestries, leaving a gap in understanding of the genetic influences in non-European populations. This study seeks to identify potential genetic variants linked to early menopause in Iranian women.
Research Design And Methods: We conducted a genome-wide association study on early menopause involving a discovery group of 3421 women, comprising 3145 individuals with normal age at menopause and 276 with early menopause.
BMC Anesthesiol
August 2025
West China School of Medicine and West China Hospital, Sichuan University, Chengdu, China.
Background: The efficacy of dexmedetomidine in preventing postoperative delirium (POD) following cardiac surgery remains controversial. This systematic review aimed to evaluate whether dexmedetomidine could prevent POD in patients undergoing cardiac surgery.
Methods: PubMed, CENTRAL, and Embase were searched up to 1 November 2024.
BMJ Open
August 2025
Department of Respiratory Medicine, JSS Medical College, Mysuru, Karnataka, India.
Introduction: Air pollution is a significant global health concern, with studies from the USA and Europe linking long-term exposure to respiratory issues and poor school attendance in children. While Indian cities experience much higher pollution levels, the impact on lung development in Indian children remains unclear. This study aims to assess the burden of impaired lung function in Indian children and identify key factors contributing to pollution-induced lung injury.
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