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Objective: The aim of the study is to investigate the association of sociodemographic factors, lifestyle, work organization, and professional profile with work ability in professional drivers.
Methods: This is a cross-sectional study with 449 drivers in Curitiba, Paraná (Brazil). Participants were assessed regarding their work ability (Work Ability Index [WAI]), sociodemographic, lifestyle (physical activity [Baecke's questionnaire] and stress [Work Stress Scale]), work organization, and professional profile using self-completion instruments. The association of WAI with sociodemographic factors, lifestyle, work organization, and professional profile was determined by multivariable ordinal logistic regression models.
Results: Lifestyle factors best explained the WAI variability. The WAI was inversely associated with stress and occupational physical activities but directly associated with leisure activities and locomotion and leisure-time physical exercise.
Conclusions: Our data also challenge the concept that sociodemographic information and ergonomics organization influence determining the work ability of this population.
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http://dx.doi.org/10.1097/JOM.0000000000002918 | DOI Listing |
BMC Health Serv Res
September 2025
Institute of General Practice, Rostock University Medical Center, Doberaner Str. 142, Rostock, 18057, Germany.
Background: Post-viral syndromes, including long- and post-COVID, often lead to persistent symptoms such as fatigue and dyspnoea, affecting patients' daily lives and ability to work. The COVI-Care M-V trial examines whether interprofessional, patient-centred teleconsultations, initiated by general practitioners in cooperation with specialists, can help reduce symptom burden and improve care for patients.
Methods: To evaluate the effectiveness of the intervention under routine care conditions, a cluster-randomised controlled trial is being conducted.
Lipids Health Dis
September 2025
Department of Gastroenterology, Weifang People's Hospital, The First Affiliated Hospital of Shandong Second Medical University, 151 Guangwen Street, Weifang, Shandong, 261000, China.
Background: Current scoring systems for hypertriglyceridaemia-induced acute pancreatitis (HTG-AP) severity are few and lack reliability. The present work focused on screening predicting factors for HTG-SAP, then constructing and validating the visualization model of HTG-AP severity by combining relevant metabolic indexes.
Methods: Between January 2020 and December 2024, retrospective clinical information for HTG-AP inpatients from Weifang People's Hospital was examined.
Nat Biotechnol
September 2025
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.
Antibody-drug conjugates (ADCs) are effective targeted therapeutics but are limited in their ability to incorporate less-potent payloads, varied drug mechanisms of action, different drug release mechanisms and tunable drug-to-antibody ratios. Here we introduce a technology to overcome these limitations called 'antibody-bottlebrush prodrug conjugates' (ABCs). An ABC consists of an IgG1 monoclonal antibody covalently conjugated to the terminus of a compact bivalent bottlebrush prodrug that has payloads bound through cleavable linkers and polyethylene glycol branches.
View Article and Find Full Text PDFACS Nano
September 2025
Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, United States.
Achieving high performance nanoscale photonic functionalities remains extraordinarily challenging when using naturally derived biomaterials. The ability to manipulate ultrathin films of structural proteins─combined with photolithographic control of their polymorphism─unlocks a compelling route toward engineering biopolymer-based photonic crystals with precisely defined photonic bandgaps and reconfigurable structural colors. In this work, we describe a robust, water-based fabrication process for silk/inorganic hybrid one-dimensional (1D) photonic crystals that overcomes many of the conventional difficulties in ensuring reproducibility, uniformity, and reliability at the nanoscale.
View Article and Find Full Text PDFISA Trans
August 2025
Department of Vehicle Engineering and Jiangsu Engineering Research Center of Vehicle Distributed Drive and Intelligent Wire Control Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Department of Vehicle Engineering and Jiangsu Engineering Research Center of Vehi
The steer-by-wire (SbW) system, as the core component of vehicle steering, needs to track the front wheel angle accurately. To mitigate the angle tracking accuracy degradation caused by D-Q axes coupling, time-varying motor electrical parameters, and load disturbance, a fractional-order adaptive fuzzy decentralized tracking control (FAFDTC) strategy is proposed in this paper. First, considering time-varying motor parameters, D-Q axes coupling, and fractional-order characteristics of components, a fractional-order SbW interconnected system is constructed to enhance its ability to characterize nonlinearities, time-varying dynamics, and system coupling.
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