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http://dx.doi.org/10.1093/ibd/izad118 | DOI Listing |
Background: Accurate identification of the mode of transmission (MoT) of HIV is critical for effective prevention. However, stigma associated with behaviors such as injecting drug use (IDU) and sex between men (MSM) can lead to misclassification of MoT data. This study replicates the methodology used in Ukraine to assess MoT misclassification and trends in Kyrgyzstan, with the aim of informing evidence-based epidemic control strategies.
View Article and Find Full Text PDFVaccines (Basel)
June 2025
Department of Radiation Oncology, Ordensklinikum Linz Barmherzige Schwestern, 4010 Linz, Austria.
: The COVID-19 pandemic significantly threatened cancer patients and oncologic care. The rollout of vaccines emerged as a critical milestone, despite the initial lack of evidence regarding their safety and efficacy in this population. This systematic review and meta-analysis evaluate the current evidence on COVID-19 vaccination in patients undergoing radiotherapy (RT).
View Article and Find Full Text PDFJ Med Virol
August 2025
Department of Hepatology, Qilu Hospital of Shandong University, Jinan, Shandong Province, PR China.
The management of chronic hepatitis B (CHB) encounters challenges like suboptimal antiviral response and the lack of predictive biomarkers. In this study, the role of paternally expressed gene 10 (PEG10) in hepatitis B e antigen (HBeAg) seroconversion (HBeAg SC) was explored to identify a therapeutic target and predictive model. In total, 349 participants were recruited, and 141 HBeAg-positive patients were followed up after 48 weeks of antiviral therapy.
View Article and Find Full Text PDFInfect Dis Ther
August 2025
Department of Nursing, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, China.
Introduction: The coexistence of hepatitis B virus (HBV) infection and metabolic dysfunction-associated fatty liver disease (MAFLD) is becoming increasingly common. The bidirectional interaction between persistent HBV infection and lipotoxicity may influence the progression of the disease. However, to date, there has been a lack of meta-analyses that stratify this dual-disease population based on the severity of MAFLD.
View Article and Find Full Text PDFBlood Adv
August 2025
Servei d'Hematologia, Vall d'Hebron Hospital Universitari, Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Despite advances in vaccination and the use of antiviral treatments, patients with hematologic malignancies, including B-cell lymphoproliferative disorders, are particularly vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The recent introduction of bispecific antibodies (BsAbs) in the treatment algorithm of relapsed/refractory B-cell non-Hodgkin lymphoma (B-NHL) has raised concerns regarding their impact on COVID-19 outcomes. This study aimed to evaluate the impact of SARS-CoV-2 infection on treatment outcomes in patients receiving BsAbs.
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