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http://dx.doi.org/10.1016/j.jbspin.2023.105601 | DOI Listing |
BMC Rheumatol
July 2025
Department of Medicine, Faculty of Medicine and Allied Medical Sciences, An-Najah National University, Nablus, Palestine.
Background: Behçet's Disease (BD) is a chronic, systemic vasculitis of unknown etiology that affects multiple organ systems. It is characterized by recurrent oral and genital ulcers, ocular involvement, affecting arteries and veins of all sizes. It is more prevalent in countries along the ancient Silk Road.
View Article and Find Full Text PDFFront Immunol
July 2025
Rheumatology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
Introduction: Behçet's syndrome (BS) is a rare systemic vasculitis. Clinical manifestations in BS are frequently clustered rather than discrete, and the concept that distinct clinical phenotypes may exist in BS has recently emerged. The aim of the present work was to identify and analyze the disease phenotypes in a monocentric historical cohort of patients with BS.
View Article and Find Full Text PDFCureus
August 2024
Dentistry, King Saud University, Riyadh, SAU.
Behçet's syndrome is a complex chronic inflammatory disorder characterized by widespread inflammation of the blood vessels, affecting various systems in the body. Although its exact cause remains unknown, genetic predisposition, particularly HLA-B51/B5 gene carriage, and environmental factors are believed to play roles. The disease typically manifests in individuals aged 20-40 years, with an uncommon occurrence in children and elderly individuals.
View Article and Find Full Text PDFCureus
July 2024
Neurology, Saint Louis University School of Medicine, Saint Louis, USA.
Behçet's disease is a rare multisystemic vasculitis characterized by oral ulcers, genital ulcers, and skin and ocular lesions. Neuro-Behçet's syndrome is a condition in which individuals with Behçet's disease experience neurological symptoms that cannot be attributed to other neurological diseases. We present a rare case of neuro-Behçet's syndrome with acute internuclear ophthalmoplegia and deteriorating neurological function with a prior history of recurrent oral ulcers with pathergy-like features, acneiform papulopustular rash, retinal hemorrhages, and recurrent epididymitis without genital ulcers.
View Article and Find Full Text PDFClin Rheumatol
October 2024
Department of Clinical Immunology and Rheumatology, St. John's Medical College Hospital, Sarjapur Road, Bengaluru, India, 560034.
Background: Behcet's disease (BD) has a heterogeneous and unpredictable phenotype that differs in various geographical areas.
Objective: To describe the clinical phenotype & outcome of Behcet's disease(BD) from Karnataka, India and compare them with large cohorts from endemic regions.
Methods: Databases of practising rheumatologists from Karnataka were reviewed to retrieve clinical characteristics, course of illness, prescribing information and outcome at last follow-up of patients clinically diagnosed as BD.