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Plastics are widely employed in modern civilization because of their durability, mold ability, and light weight. In the recent decade, micro/nanoplastics research has steadily increased, highlighting its relevance. However, contaminating micro/nanoplastics in marine environments, terrestrial ecosystems, and biological organisms is considered a severe threat to the environmental system. Geographical distribution, migration patterns, etymologies of formation, and ecological ramifications of absorption are just a few topics covered in the scientific literature on environmental issues. Degradable solutions from material science and chemistry are needed to address the micro/nanoplastics problem, primarily to reduce the production of these pollutants and their potential effects. Removing micro/nanoplastics from their discharge points has been a central and effective way to mitigate the adverse pollution effects. In this review, we begin by discussing the hazardous effect on living beings and the identification-characterization of micro/nanoplastics. Then, we provide a summary of the existing degradation strategies, which include bio-degradation and advanced oxidation processes (AOPs), and a detailed discussion of their degradation mechanisms is also represented. Finally, a persuasive summary of the evaluated work and projections for the future of this topic is provided.
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http://dx.doi.org/10.1016/j.etap.2023.104193 | DOI Listing |
Syst Biol Reprod Med
December 2025
Department of Zoology (Post Graduate Studies), Rishi Bankim Chandra College, Affiliated to West Bengal State University, Naihati, India.
Indiscriminate use of polystyrene (PS) plastics has posed a major problem for its disposal and recycling on one hand, while on the other hand, fragmentation of these into micro/nano compounds threatens the living world by its toxic effect. The small sized particles can be present in any ecosystem and pose threat to the living world there. The unique properties of these small-scale fragments allow them to cross the barriers of human bodies and affect the vital organ system, altering the normal physiological parameters.
View Article and Find Full Text PDFToxicology
August 2025
School of Environmental Engineering, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul 02504, Republic of Korea. Electronic address:
Micro/nanoplastics (MNPs), detected in human tissues including the placenta, raise significant concerns regarding their potential impact on early human development. However, the mechanisms underlying their developmental toxicity remain poorly understood. To address this, we applied an Integrated Approaches to Testing and Assessment (IATA) framework to evaluate the developmental toxicity of polystyrene (PS) MNPs by combining adverse outcome pathway (AOP) development, experimental testing within an Integrated Testing Strategy (ITS), and literature-based data integration.
View Article and Find Full Text PDFJ Hazard Mater
August 2025
Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210009, China. Electronic address:
Infusion therapy represents a critical and emerging exposure pathway for micro/nanoplastics (MNPs), with significant implications for human health. However, accurate and simultaneous analytical methods for MNPs in infusion solutions are still underdeveloped, and the potential co-exposure to MNPs and phthalates (PAEs) has not been fully explored. This study presents a novel integrated analytical approach combining Cloud-Point Extraction with Pyrolysis-Thermal Desorption-Gas Chromatography-Mass Spectrometry, enabling efficient extraction and precise quantification of MNPs from commonly used glucose and saline infusions, with MNP recovery rates ranging from 96.
View Article and Find Full Text PDFNanoImpact
August 2025
Institute of Pesticide and Environmental Toxicology, Ministry of Agriculture and Rural Affairs Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, College of Agricultural and Biotechnology, Zhejiang University, Hangzhou 310058, China. Electronic address:
Micro/nanoplastics (MNPs) commonly coexist with contaminants such as heavy metals and antibiotics in aquatic environments, potentially inducing complex joint toxicity. However, conventional approaches for MNP-pollutant combined toxicity assessment are typically challenged by inefficiencies, high costs, and labor-intensive procedures. In this study, a high-throughput platform using microplate-based inhibition assays with a luminescent bacterium (Vibrio qinghaiensis sp.
View Article and Find Full Text PDFEur J Histochem
June 2025
Section of Histology and Embryology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia; Regenerative Medicine Research Center, Fondazione IRCCS Policlinico San Matteo, Pavia.
The statement "Plastics define the way we live today" summarizes the findings of the Plastic Europe 2020 final document (https://plasticseurope.org/knowledge-hub/plastics-the-facts-2020/). Sadly, this also means that the plastic waste generated over the next decade is likely to become unmanageable.
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