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The most important descending thoracic aortic (DTA) pathologies are aneurysms, dissections, and traumatic injuries. In acute settings, these conditions can constitute a significant risk of bleeding or ischemia of vital organs, resulting in a fatal outcome. Morbidity and mortality associated with aortic pathologies remain significant, despite improvements in medical therapy and endovascular techniques. In this narrative review, we present an overview of the transitions in the management of these pathologies and discuss current challenges and future perspectives. Diagnostic challenges include differentiating between thoracic aortic pathologies and cardiac diseases. Efforts have been made to identify a blood test that can rapidly differentiate these pathologies. Computed tomography is the cornerstone of diagnosing thoracic aortic emergencies. Our understanding of DTA pathologies has improved substantially due to the significant advancement in imaging modalities in the last 2 decades. On the basis of this understanding, the treatment of these pathologies has been revolutionized. Unfortunately, robust evidence from prospective and randomized studies is still lacking for the management of most DTA diseases. Medical management plays a crucial role in achieving early stability during these life-threatening emergencies. This includes intensive care monitoring, heart rate and blood pressure control, and considering permissive hypotension for patients presenting with ruptured aneurysms. Over the years, surgical management of DTA pathologies changed from open repair to endovascular repair with dedicated stent-grafts. Techniques in both spectrums have improved substantially.
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http://dx.doi.org/10.1053/j.semvascsurg.2023.04.009 | DOI Listing |
Turk Kardiyol Dern Ars
September 2025
Department of Cardiology, Muğla Sıtkı Koçman University, School of Medicine, Muğla, Türkiye.
Objective: Management of aortic stenosis (AS) requires integrating complex clinical, imaging, and risk stratification data. Large language models (LLMs) such as ChatGPT and Gemini AI have shown promise in healthcare, but their performance in valvular heart disease, particularly AS, has not been thoroughly assessed. This study systematically compared ChatGPT and Gemini AI in addressing guideline-based and clinical scenario questions related to AS.
View Article and Find Full Text PDFDiabetes Obes Metab
September 2025
Epidemiology, IQVIA, Frankfurt, Germany.
Aims: To examine the association between elevated body mass index (BMI) and a wide range of vascular and cardiometabolic diseases in men and women.
Materials And Methods: This retrospective cohort study used data from the IQVIA Disease Analyzer database, comprising anonymized records from over 3000 office-based physicians in Germany. We included 233 730 patients aged ≥40 years with at least one recorded BMI measurement between January 2005 and December 2023.
J Vasc Surg Cases Innov Tech
December 2025
Faculdade de Ciências Médicas de Alagoas, Vascular and Endovascular Surgery Division, Alagoas, Alagoas, Brazil.
Background: Iatrogenic thoracic aortic injury (TAI) is a rare but well-recognized complication of spine surgery, lacking standardized treatment guidelines due to its rarity and variability of manifestations.
Methods: We present a new case of TAI successfully managed with endovascular repair and systematically reviewed 52 articles (1991-2024) reporting 64 cases, including demographics, surgical indications, injury patterns, and treatments.
Results: A 53-year-old man with a T7 fracture underwent posterior spinal instrumentation and developed chest pain due to a combination of impingement and screw penetration into the thoracic aorta and was treated with thoracic endovascular aortic repair (TEVAR) and removal of pedicle screws.
Front Oncol
August 2025
Department of Gastroenterology, Shaanxi Provincial People's Hospital, Xi'an, China.
Background: Azygos vein aneurysm (AVA) is a rare thoracic pathology that is frequently misdiagnosed. While contrast-enhanced chest computed tomography (CT) or magnetic resonance imaging (MRI) can delineate AVA location and size, these techniques lack the capability for dynamic real-time assessment of internal architecture.
Case Presentation: We present a highly unusual case of a 67-year-old woman who had an isolated azygos vein aneurysm presenting with dysphagia.
Am J Prev Cardiol
September 2025
Tsimane Health and Life History Project, San Borja, Bolivia.
Background: Greater deposits of epicardial adipose tissue are associated with atrial fibrillation and coronary disease, but have not been studied in subsistence populations.
Methods: We performed CT imaging to measure coronary artery and thoracic aortic calcium (CAC, TAC), epicardial fat thickness (EFT), liver density, and left atrial (LA) anteroposterior diameter and, using a deep learning-enabled software program, epicardial and thoracic fat volume (EFV, TFV), in two remote Amerindian subsistence populations with minimal coronary artery calcification and virtually no atrial fibrillation. We compared 893 adult Tsimane (mean age 58.