The Scottish inflammatory prognostic score: A novel biomarker for predicting in-hospital mortality in acute heart failure with reduced ejection fraction.

Background: Acute heart failure with reduced ejection fraction (AHF) remains a leading cause of ED visits, hospitalizations, and in-hospital mortality.

Objectives: To evaluate the prognostic utility of the Scottish Inflammatory Prognostic Score (SIPS) in patients with AHF.

Methods: This retrospective study analyzed 508 patients admitted with AHF between November 2022 and November 2024.

Active Side-Branch Protection Strategy for Culprit Bifurcation Lesion in STEMI Patients: The Multicenter STEMI-BIF Registry.

Background: To date, the best side branch (SB) protection strategy in patients with coronary bifurcation lesions (CBLs)-related ST-segment elevation myocardial infarction (STEMI) has not yet been settled.

Aims: This study sought to evaluate the clinical outcome of the jailed balloon (JBT) and jailed wire techniques (JWT) for the SB protection strategy in STEMI patients with culprit CBLs.

Methods: This large-scale multicenter (n = 10) observational retrospective study included STEMI patients with culprit CBLs who underwent PCI with provisional stenting.

Ostial Stent Implantation or Crossover Stenting for Ostial LAD Lesions: The Multicenter CROSS-ANATOLIA Registry.

Percutaneous coronary intervention (PCI) for isolated ostial left anterior descending artery (LAD) lesions remains technically difficult. Accurate ostial stenting (AOS) aims to prevent involvement of the left main coronary artery (LMCA), while crossover stenting (COS) ensures complete ostial coverage but may increase procedural complexity. This study aimed to evaluate the long-term outcomes of patients who underwent AOS or COS for ostial LAD disease.

Double kissing culotte or mini-crush stenting for true coronary bifurcation lesions: the multicenter COLLECT-BIF registry.

Background: This multicenter observational study aimed to retrospectively evaluate the mid-term clinical outcomes of the mini-crush technique (MCT) and double kissing culotte technique (DKCT) in patients with coronary bifurcation lesions (CBLs).

Methods: This large-scale, multicenter study (n = 8) included patients with CBLs who underwent percutaneous coronary intervention with either MCT or DKCT. The primary endpoint was defined as major adverse cardiac events (MACE), which include cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization.

Association of controlling nutritional status score and long-term mortality in acute pulmonary embolism.

Background And Aims: Pulmonary embolism (PE) is a life-threatening condition with significant short- and long-term mortality risk. Although existing risk stratification models focus on short-term outcomes, the role of nutritional status in predicting long-term mortality remains underexplored. This retrospective study investigated the prognostic value of the Controlling Nutritional Status (CONUT) score, a composite index derived from serum albumin, total cholesterol, and lymphocyte counts.

Athlete's Heart in Women's Contact Sports: Echocardiographic and Strain-Based Insights From Elite Rugby Players.

Background: Athlete's heart encompasses cardiac adaptations to long-term intensive training. Although male-dominated sports have been widely studied, limited data exist on structural and functional cardiac remodeling in female contact-sport athletes. This study aimed to evaluate cardiac changes in elite female rugby players using conventional and strain echocardiography.

A Novel Non-invasive Marker for Predicting Mechanical Prosthetic Heart Valve Thrombosis: Red Cell Distribution Width to Platelet Ratio.

BackgroundProsthetic heart valve thrombosis (PHVT) is a serious and potentially life-threatening complication that affects patients with mechanical heart valves. Timely and precise prediction of PHVT is essential for prompt intervention. This study aims to assess the association between the ratio of red blood cell distribution width (RDW) and platelet (PLT) count with PHVT.

The monocyte-to-HDL-cholesterol ratio predicts new-onset atrial fibrillation in patients with acute STEMI.

Objective: Newly diagnosed AF (NOAF) associated with acute STEMI holds significant relevance in clinical practice. This study seeks to assess the role of the monocyte to HDL-C ratio (MHR) in predicting NOAF in these patients.

Methods: Between July 2017 and May 2018, 663 patients who underwent primary PCI for STEMI were retrospectively analyzed.

The impact of bifurcation angle on clinical outcomes in patients who underwent nano-crush technique: the insight from the multicenter EVOLUTE-CRUSH V study.

Background: This multicenter study aimed to retrospectively assess the relationship between bifurcation angle (BA) and major cardiovascular events (MACEs) in patients undergoing nano-crush technique (NCT) for complex bifurcation lesions (CBLs).

Methods: A total of 122 consecutive patients [male: 85 (69.6%), mean age: 61.

The Association Between Left Ventricular Global Function Index and Major Adverse Cardiovascular Events Linked to Systemic Inflammation in Acute Coronary Syndrome.

We aimed to investigate the association between systemic inflammation and the left ventricular global function index (LVGFI) and evaluate the diagnostic performance of LVGFI for MACEs across the acute coronary syndrome (ACS) spectrum. A total of 1697 patients (794 with ST-segment elevation myocardial infarction [STEMI] and 903 with non-STEMI [NSTEMI]) were evaluated. The LVGFI was calculated using echocardiography.

Mini-crush or Nano-crush Stenting Technique for Complex Coronary Bifurcation Lesions: the Multicenter MINANO Registry.

Background: In this multicenter study we aimed to retrospectively identify the midterm clinical outcomes of the mini-crush technique (MCT) and nano-crush technique (NCT) in patients with complex bifurcation lesions (CBLs).

Methods: The study included 431 patients (318 men [73.8%], mean age 60.

Echocardiographic Evaluation of the Effect of Long-Term Methylphenidate Use on Cardiovascular Functions.

Objective: ADHD is one of the most common neurodevelopmental disorders, seen in children and adolescents, and is often treated with various pharmacological agents, especially methylphenidate. There are differing opinions in the literature regarding the cardiovascular safety of long-term methylphenidate use. Studies suggest that the drug may increase the risk of hypertension, myocardial infarction, ventricular arrhythmia, sudden cardiac death, cardiomyopathy, heart failure (HF), pulmonary hypertension, and stroke.

Cardiovascular outcomes of complex bifurcation lesions following double kissing crush or nano-crush techniques: The multicenter EVOLUTE-CRUSH V study.

Background: Double kissing crush (DKC) and nano-crush (NC) techniques are frequently used, but the comparison for both techniques is still lacking. The goal of this multicenter study was to retrospectively assess the midterm clinical results of DKC and NC stenting in patients with complex bifurcation lesions (CBLs).

Methods: A total of 324 consecutive patients [male: 245 (75.