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Application of continuous glucose monitoring (CGM) has moved diabetes care from a reactive to a proactive process, in which a person with diabetes can prevent episodes of hypoglycemia or hyperglycemia, rather than taking action only once low and high glucose are detected. Consequently, CGM devices are now seen as the standard of care for people with type 1 diabetes mellitus (T1DM). Evidence now supports the use of CGM in people with type 2 diabetes mellitus (T2DM) on any treatment regimen, not just for those on insulin therapy. Expanding the application of CGM to include all people with T1DM or T2DM can support effective intensification of therapies to reduce glucose exposure and lower the risk of complications and hospital admissions, which are associated with high healthcare costs. All of this can be achieved while minimizing the risk of hypoglycemia and improving quality of life for people with diabetes. Wider application of CGM can also bring considerable benefits for women with diabetes during pregnancy and their children, as well as providing support for acute care of hospital inpatients who experience the adverse effects of hyperglycemia following admission and surgical procedures, as a consequence of treatment-related insulin resistance or reduced insulin secretion. By tailoring the application of CGM for daily or intermittent use, depending on the patient profile and their needs, one can ensure the cost-effectiveness of CGM in each setting. In this article we discuss the evidence-based benefits of expanding the use of CGM technology to include all people with diabetes, along with a diverse population of people with non-diabetic glycemic dysregulation.
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http://dx.doi.org/10.1007/s13300-023-01431-3 | DOI Listing |
NMR Biomed
October 2025
High-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
The human kidneys play a pivotal role in regulating blood pressure, water, and salt homeostasis, but assessment of renal function typically requires invasive methods. Deuterium metabolic imaging (DMI) is a novel, noninvasive technique for mapping tissue-specific uptake and metabolism of deuterium-labeled tracers. This study evaluates the feasibility of renal DMI at 7-Tesla (7T) to track deuterium-labeled tracers with high spatial and temporal resolution, aiming to establish a foundation for potential clinical applications in the noninvasive investigation of renal physiology and pathophysiology.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
September 2025
Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, QC, Canada. Electronic address:
This chapter, "Implantable Biosensors: Advancements and Applications," provides a succinct overview of the state-of-the-art in implantable biosensor technology, highlighting both established clinical uses and promising areas of ongoing research. It begins by outlining the fundamental principles and advantages of these sensors, such as their precision in physiological monitoring and capability for real-time therapeutic interventions. A variety of implantable sensors are categorized, including biophysical and biochemical types, each designed for specific medical applications.
View Article and Find Full Text PDFDiabetes Metab Syndr Obes
August 2025
Diabetes Centre, Second Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Recreational diving with self-contained underwater breathing devices is gaining popularity worldwide as a sport and leisure activity. People living with type 1 diabetes mellitus (PLT1D) are no exception, although historically diabetes mellitus, especially insulin-treated, has been described as an absolute contra-indication for diving. However, based on observational data collected by the Divers Alert Network, the presence of background diabetes mellitus became only a relative contraindication for those without significant co-morbidities or long-term complications.
View Article and Find Full Text PDFDiabetes Technol Ther
September 2025
Department of Genetics, Stanford University, Stanford, California, USA.
Continuous glucose monitoring (CGM) devices provide real-time actionable data on blood glucose levels, making them essential tools for effective glucose management. Integrating blood glucose data with food log data is crucial for understanding how dietary choices impact glucose levels. Despite their utility, many CGM applications lack integration with other external services, such as food trackers, and do not generate useful glycemic variability (GV) metrics or advanced visualizations.
View Article and Find Full Text PDFJ Diabetes Res
September 2025
Department of Medicine, Mahidol University Faculty of Medicine Siriraj Hospital, Bangkok, Thailand.
This study is aimed at evaluating the accuracy and feasibility of real-time continuous glucose monitoring (rt-CGM) in non-ICU hospitalized adult COVID-19 patients who had hyperglycemia requiring insulin therapy during admission. Medtronic Guardian Sensor 3 and transmitter were placed on the patient's abdomen. The patient performed a self-calibration of CGM via the application installed in the smartphone.
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