98%
921
2 minutes
20
This study examined the phytochemical profiles (mainly phenolics, carotenoids, and organosulfur compounds) and biological effects of hydroalcoholic extracts of Allium flavum (AF), a species of the Allium genus commonly known as small yellow onion. Unsupervised and supervised statistical approaches revealed clear differences between extracts prepared with samples collected from different areas of Romania. Overall, the AFFF (AF flowers collected from Făget) extract was the best source of polyphenols, also showing the highest antioxidant capacity evaluated through both in vitro DPPH, FRAP, and TEAC anti-radical scavenging assays and cell-based OxHLIA and TBARS assays. All the tested extracts exhibited α-glucosidase inhibition potential, while only the AFFF extract exhibited anti-lipase inhibitory activity. The phenolic subclasses annotated were positively correlated with the assessed antioxidant and enzyme inhibitory activities. Our findings suggested that A. flavum has bioactive properties worth exploring further, being a potential edible flower with health-promoting implications.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.foodchem.2023.136503 | DOI Listing |
Perfluorinated and polyfluoroalkyl compounds (PFASs) represent a category of synthetic chemicals renowned for their environmental persistence. Owing to their hydrophobic, oleophobic, and high-temperature-resistant properties, PFASs are extensively utilized in industrial, agricultural, and civilian sectors, including applications in leather, textiles, flame-retardant materials, lubricants, and coatings, among others. PFASs can accumulate within the human body, exhibiting multi-organ toxicity.
View Article and Find Full Text PDFEmerg Microbes Infect
September 2025
Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong.
We report cases of infections on the scalp of three individuals from an African family, originating from Mali and residing in Guangzhou. This is the first time that has been reported in China. The index case involved a 2-year-old boy who presented with scalp patches and scaling for more than 1 year.
View Article and Find Full Text PDFBMC Oral Health
September 2025
Xiangya Stomatological Hospital and Xiangya School of Stomatology, Hunan Key Laboratory of Oral Health Research, Hunan Clinical Research Center of Oral Major Diseases and Oral Health, Academician Workstation for Oral-maxilofacial and Regenerative Medicine, Central South University, Changsha, 410008,
Background: Eruption sequestrum (ES) is an uncommon condition characterized by irregular calcified tissues on the occlusal surfaces of erupting permanent molars, primarily in children. Despite its rarity, ES has been linked to potential complications, including gingivitis, occlusal trauma, and delayed tooth eruption.
Case Presentation: This paper reports a multiquadrant ES case affecting the first molars of bilateral maxillary and mandibular arches in a 6-year-old pediatric patient.
Drug Saf
September 2025
Medicines and Healthcare products Regulatory Agency (MHRA), Safety and Surveillance, 10 South Colonnade, Canary Wharf, London, E14 4PU, UK.
Introduction: Yellow Card Vaccine Monitor (YCVM) was established by the UK Medicines and Healthcare products Regulatory Agency (MHRA) to facilitate active monitoring of adverse drug reactions following COVID-19 vaccination and further characterise safety in populations under-represented in clinical trials.
Objective: This study explored the profile of individuals registered to the YCVM platform and the suspected adverse drug reactions reported following a COVID-19 vaccination on this data platform.
Methods: Using a stratified random selection approach, individuals were invited to register and actively contacted to seek further information on the vaccines received and adverse reactions they experienced.
Mol Ther Nucleic Acids
September 2025
Department of Synthetic Biology and Immunology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia.
Loss-of-function mutations in the gene cause β-catenin deficiency, resulting in CTNNB1 syndrome, a rare neurodevelopmental disorder characterized by motor and cognitive impairments. Given the wide variety of mutations across and its dosage sensitivity, a mutation-independent therapeutic approach that preserves endogenous gene regulation is critically needed. This study introduces spliceosome-mediated RNA -splicing as a novel approach to restore β-catenin production.
View Article and Find Full Text PDF