98%
921
2 minutes
20
Objective: This article summarizes our approach to extracting medication and corresponding attributes from clinical notes, which is the focus of track 1 of the 2022 National Natural Language Processing (NLP) Clinical Challenges(n2c2) shared task.
Methods: The dataset was prepared using Contextualized Medication Event Dataset (CMED), including 500 notes from 296 patients. Our system consisted of three components: medication named entity recognition (NER), event classification (EC), and context classification (CC). These three components were built using transformer models with slightly different architecture and input text engineering. A zero-shot learning solution for CC was also explored.
Results: Our best performance systems achieved micro-average F1 scores of 0.973, 0.911, and 0.909 for the NER, EC, and CC, respectively.
Conclusion: In this study, we implemented a deep learning-based NLP system and demonstrated that our approach of (1) utilizing special tokens helps our model to distinguish multiple medications mentions in the same context; (2) aggregating multiple events of a single medication into multiple labels improves our model's performance.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10527481 | PMC |
http://dx.doi.org/10.1016/j.jbi.2023.104391 | DOI Listing |
Patient
September 2025
PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, Waltham, MA, USA.
Background: Migraine care is often suboptimal owing to undertreatment, variation in clinical outcomes and administration methods among existing treatments, and between- and within-individual heterogeneity in the clinical course of migraine. In response to these challenges, preference studies have been increasingly conducted to inform treatment decision-making and development. However, gaps remain in understanding how treatment preferences have been assessed across different migraine studies.
View Article and Find Full Text PDFDiabetologia
September 2025
Centre Universitaire de Diabétologie et de ses Complications, AP-HP, Hôpital Lariboisière, Paris, France.
Aims/hypothesis: Severe hypoglycaemia events (SHE) remain frequent in people with type 1 diabetes despite advanced diabetes technologies. We examined whether time below range (TBR) 3.9 mmol/l (70 mg/dl; TBR70) or 3.
View Article and Find Full Text PDFJ Gerontol A Biol Sci Med Sci
September 2025
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, USA.
Maintenance of organismal function requires tightly regulated biomolecular communication. However, with aging, communication deteriorates, thereby disrupting effective information flow. Using information theory applied to skeletal muscle single cell RNA-seq data from young, middle-aged, and aged animals, we quantified the loss of communication efficiency over time.
View Article and Find Full Text PDFJ Gambl Stud
September 2025
Department of Psychiatric Nursing, Faculty of Health Sciences, Eskisehir Osmangazi University, Eskisehir, Türkiye.
The aim of this study is to evaluate the readability and reliability of websites providing information about gambling. The study assessed 65 Turkish-language websites from Google. In this study, readability was assessed using the Ateşman Readability Index, which determines textual difficulty based on sentence and word length.
View Article and Find Full Text PDFFront Oncol
August 2025
Department of Gynecology, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Ovarian cancer (OC) and uterine cancer (UC) are significant public health concerns among women of reproductive age. High body mass index (BMI) contributes to the increasing burden of these cancers globally, but comprehensive epidemiological assessments remain limited.
Methods: Data were obtained from the Global Burden of Disease (GBD) Study 2021 (1990-2021).