98%
921
2 minutes
20
This study examined the association of gestational diabetes mellitus (GDM), prenatal, and postnatal maternal depressive symptoms with externalizing, internalizing, and autism spectrum problems on the Preschool Child Behavior Checklist in 2379 children aged 4.12 ± 0.60 (48% female; 47% White, 32% Black, 15% Mixed Race, 4% Asian, <2% American Indian/Alaskan Native, <2% Native Hawaiian; 23% Hispanic). Data were collected from the NIH Environmental influences on Child Health Outcomes (ECHO) Program from 2009-2021. GDM, prenatal, and postnatal maternal depressive symptoms were each associated with increased child externalizing and internalizing problems. GDM was associated with increased autism behaviors only among children exposed to perinatal maternal depressive symptoms above the median level. Stratified analyses revealed a relation between GDM and child outcomes in males only.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620104 | PMC |
http://dx.doi.org/10.1111/cdev.13938 | DOI Listing |
Arch Med Res
September 2025
Department of Structural and Functional Biology, Institute of Biosciences, São Paulo State University, Botucatu, SP, Brazil. Electronic address:
Background: Phthalates are compounds used as plasticizers to increase the flexibility of plastics and are considered endocrine disruptors. Some studies suggest that the origin of prostate cancer (PCa) may be associated with disturbances during embryo-fetal development. Previous data showed that perinatal exposure to the same phthalate mixture (PM) used here increased the incidence of adenocarcinomas in the prostates of aged rats.
View Article and Find Full Text PDFHum Reprod Update
September 2025
Women's Health Research Collaborative, New York, NY, USA.
Background: Reproductive-age women with intrauterine adhesions (IUAs) following uterine surgery may be asymptomatic or may experience light or absent menstruation, infertility, preterm delivery, and/or peripartum hemorrhage. Understanding procedure- and technique-specific risks and the available evidence on the impact of surgical adjuvants is essential to the design of future research.
Objective And Rationale: While many systematic reviews have been published, most deal with singular aspects of the problem.
Ann Rheum Dis
September 2025
Department of Radiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Objectives: This study aims to evaluate the evolution of subchondral sacroiliac joint (SIJ) sclerosis from pregnancy to 12 months postpartum, and to explore preceding and concomitant magnetic resonance imaging (MRI) features, potentially indicating osteitis condensans ilii (OCI).
Methods: One hundred three first-time mothers were recruited for serial SIJ MRIs. MRI scans were performed at pregnancy weeks 20 and 32, and at 3, 6, and 12 months postpartum.
J Affect Disord
September 2025
Department of emergency, West China Second University Hospital, Sichuan University, Chengdu, 610041, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, 610041, China; Department of Emergency, Chengdu Hi-Tech Zone Ho
Background: Studies examining the association between maternal antibiotic use during pregnancy and the risk of childhood attention-deficit/hyperactivity disorder (ADHD) have yielded inconsistent results. This meta-analysis synthesizes available evidence to establish a more comprehensive understanding of this association.
Methods: Observational studies published through October 2, 2024, were systematically searched from Cochrane Library, EMBASE, Web of Science, and PubMed databases.
J Affect Disord
September 2025
Department of Psychology, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute (ACHRI), Calgary, AB, Canada; Department of Educational and Counselling Psychology, and Special Education (ECPS), University of British Columbia, BC, Canada.
Background: Perinatal depression has been linked to higher negative affectivity (NA) in children, though the strength of this association is variable. Infant sleep, a known protective factor, may moderate this relationship though this has not been tested.
Objective: To examine whether within-person changes in depressive symptoms across pregnancy and postpartum were linked to child NA, and whether infant sleep duration moderated these effects.