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Hepatitis of undetermined origin can be caused by a wide variety of pathogens, sometimes emerging pathogens. We report the discovery, by means of routine shotgun metagenomics, of a new virus belonging to the family Circoviridae, genus Circovirus, in a patient in France who had acute hepatitis of unknown origin.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124635 | PMC |
http://dx.doi.org/10.3201/eid2905.221485 | DOI Listing |
Front Vet Sci
August 2025
Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, United States.
Canine Infectious Respiratory Disease Complex (CIRDC), caused by a diverse range of viral and bacterial pathogens, is the leading cause of respiratory illness in dogs. In the winter of 2023-2024, the United States experienced a noticeable increase in cases consistent with CIRDC. This study investigated the potential association of emerging pathogens with CIRDC cases.
View Article and Find Full Text PDFJ Virol
June 2025
College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis and nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure. The PCV3 capsid (Cap) protein interacts with DEAD-box RNA helicase 10 (DDX10), a protein that functions primarily through regulating interferon (IFN)-β production to exert its antiviral activity. However, how the interaction between DDX10 and PCV3 Cap regulates viral replication remains unknown.
View Article and Find Full Text PDFMicrob Pathog
August 2025
ICAR-ICFMD-National Institute on Foot and Mouth Disease, Bhubaneswar, Odisha, India.
M. hyopneumoniae is an atypical bacterium that is frequently associated with porcine enzootic pneumonia, but uncommonly identified as a cause of pericarditis and myocarditis leading to pericardial tamponade. The present report describes the rare case of M.
View Article and Find Full Text PDFViruses
January 2025
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis, nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure. The PCV3 capsid (Cap) protein interacts with DDX21, which functions mainly through controlling interferon (IFN)-β levels. However, how the interaction between DDX21 and PCV3 Cap regulates viral replication remains unknown.
View Article and Find Full Text PDFAnimals (Basel)
February 2025
Departamento de Medicina Animal, Unidad de Anatomía Patológica y Anatomía Comparada, Facultad de Veterinaria de Cáceres, Universidad de Extremadura, 10003 Cáceres, Spain.
PCV-3 and PCV-4 are novel viruses that can infect domestic pigs and wild boars. Both viruses are associated with multiple disorders in domestic pigs (reproductive failure, respiratory damage, etc.).
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