PCV-2 vaccination modifies the cytokine serum profile in wild boar (Sus scrofa) coinfected with tuberculosis and PCV-2.

Animal tuberculosis (TB) and porcine circovirus 2 (PCV-2) coinfections have been associated to the development of severe patterns of tuberculous lesions. These coinfections are frequently observed in wild boar, considered the main wild reservoir of TB in Spain. The vaccination of wild boar with a single dose of PCV-2 vaccine has been associated with less severity of lesions.

Effect of PCV-2 Vaccination on Cytokines Gene Expression Profile in Wild Boar Peripheral Blood Mononuclear Cells after Stimulation with Mycobacteria Antigens.

Wild boar () is a common wild ungulate known as the most important reservoir of tuberculosis (TB) in Spain. The severity of TB lesions in this species and the high prevalence of porcine circovirus type 2 (PCV-2) have been related. PCV-2 is ubiquitous in swine populations, being usual for the free-living ones the contact with this agent.

Significant Detection of Porcine Circovirus 3 and Porcine Circovirus 4 in Wild Boars from Mid-Western Spain Without Apparent Sanitary Consequences.

PCV-3 and PCV-4 are novel viruses that can infect domestic pigs and wild boars. Both viruses are associated with multiple disorders in domestic pigs (reproductive failure, respiratory damage, etc.).