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http://dx.doi.org/10.1002/pbc.30353 | DOI Listing |
Transpl Immunol
September 2025
Department of Pediatrics, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Background And Aim: Lung transplantation (LTx) is increasingly performed worldwide, yet post-transplant survival remains lower than for other solid organs. Diabetes mellitus (DM) is common among LTx recipients and impacts outcomes. This systematic review evaluates the effects of DM on LTx outcomes and the influence of diabetes onset timing on survival.
View Article and Find Full Text PDFBlood Adv
September 2025
Memorial Sloan Kettering Cancer Center, New York, New York, United States.
Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative option for patients with high-risk malignancies and non-malignant disorders. Long-term survival depends on robust immune reconstitution (IR), which governs overall immune homeostasis and risks of infection, graft-versus-host disease, and relapse. However, despite its centrality to post-transplant outcomes, IR is not consistently monitored across transplant centers, limiting ability to generate meaningful, comparable, and translatable data.
View Article and Find Full Text PDFRheumatology (Oxford)
September 2025
Department of Pediatric Hematology-Immunology and Rheumatology, Hôpital Necker Enfants malades, Paris, France.
Objectives: Severe forms of systemic juvenile idiopathic arthritis (sJIA), also called pediatric-onset Still's disease are associated with two major life-threatening complications: macrophage activation syndrome (MAS) and severe lung disease. Patients are usually resistant to conventional synthetic (cs) Disease-Modifying Antirheumatic Drugs (DMARDs), biologic (b) DMARDs, and targeted synthetic (ts) DMARDs. Recently, allogeneic hematopoietic stem cell transplantation (HSCT) has been performed in a small number of patients with refractory and life-threatening disease.
View Article and Find Full Text PDFPediatr Cardiol
August 2025
Division of Abdominal Transplantation, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX, USA.
School attendance is associated with increased quality of life in chronically ill pediatric patients and has a profound impact on child development. Despite the importance of school attendance, little research has been done to identify which pediatric transplant recipients are at risk for delayed school attendance due to morbidity.Despite the importance of school attendance, little research has been done to identify which pediatric transplant recipients are at risk for delayed school attendance due to morbidity.
View Article and Find Full Text PDFWorld J Transplant
September 2025
Department of Anatomy, All India Institute of Medical Sciences, Bhubaneswar 751019, Odisha, India.
Background: Not all islet transplants desirably achieve insulin independence. This can be attributed to the microarchitecture and function of the islets influenced by their dimensions. Large islets enhance insulin secretion through paracrine effects but are more susceptible to hypoxic injury post-transplant, while small islets offer better viability and insulin independence.
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