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Article Abstract

Chitinase 1 (CHIT1) plays a role in the pathogenesis of pulmonary fibrosis by modulating canonical and noncanonical TGF-β signaling via interaction with TGFBRAP1 and FOXO3. These findings highlight the CHIT1/SMAD7 axis as a potential biomarker and therapeutic target of pulmonary fibrosis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10088146PMC
http://dx.doi.org/10.26508/lsa.202302065DOI Listing

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