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Introduction: Osteoporosis is a common disease among middle-aged and older people. Because bone mineral density (BMD) is obtained by dividing bone mineral content by area, accurate measurement of the surface of the studied area plays an important role. Therefore, the purpose of this study was to investigate the area of the hip and forearm regions based on gender and height.
Methods: In a cross-sectional descriptive study of 758 individuals (702 female and 56 male, divided into 2 groups of ≥50 years old and <50 years old), experienced personnel performed densitometry of the forearm and femur using a Hologic device. The results were statistically analyzed using SPSS software version 21.
Results: In women ≥50 years old who were of white race, one-third of the forearm BMD showed moderate agreement with the femoral neck BMD, and in this group, total forearm BMD showed moderate agreement with the femoral neck BMD. In women <50 years old of Caucasian race, one-third of the forearm BMD showed good agreement with the femoral trochanter. In the same group of individuals, total forearm BMD also showed very good agreement with the femoral trochanter. In women <50 years old of white race, one-third of the forearm BMD showed good agreement with all 4 regions in the femur (trochanter, intertrochanteric, neck, total), and in the same group of individuals, total forearm BMD showed very good agreement with all 4 regions of the femur.
Conclusion: According to the results obtained for comparison of forearm one-third with hip areas, it seems that simultaneous measurement of the forearm one-third area and different hip areas increases the accuracy of total BMD measurement.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_839_22 | DOI Listing |
Clin Oral Investig
September 2025
Department of Stomatology, Shengli Oilfield Central Hospital, No. 31, Jinan Road, Dongying, 257034, China.
Objective: Progesterone (PG) and its target, progesterone receptor (PGR), are important regulators in inflammatory diseases. This study aimed to investigate the specific role of PG in periodontitis and to elucidate the underlying mechanisms involving PGR.
Methods: Women with periodontitis, including 250 with PG deficiency, 250 with PG supplementation, and 245 controls (normal PG) were enrolled.
J Orthop Sci
September 2025
Department of Orthopaedic Surgery, NHO Saga Hospital, 1-20-1 Hinode, Saga 849-0923, Japan.
Background: Hounsfield units (HU) on computed tomography (CT) are strongly correlated with bone mineral density (BMD) and may aid in osteoporosis screening. However, there is no standardized method for assessing bone density in displaced femoral head fractures. This study aimed to measure HU values in the femoral head using preoperative post-fracture CT images of patients with intertrochanteric femoral fractures and investigate whether it correlated with BMD measured by dual-energy X-ray absorptiometry (DXA).
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Shenzhen College of Advanced Technology, University of Chinese Academy of Sciences, Beijing, 100049, China; Research Center for Cancer Immunology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic
Within the bone microenvironment, the intricate interplay and regulation among matrix components form a complex network. Disentangling this network is crucial for uncovering potential therapeutic targets in bone pathology. Osteocalcin (OCN), the most abundant non-collagenous bone protein, is an essential node within this network.
View Article and Find Full Text PDFSkeletal Radiol
September 2025
Department of Radiology, Hospital do Coração (HCor), Rua Desembargador Eliseu Guilherme, 53, 7th floor. CEP, São Paulo, SP, 04004-03, Brazil.
Atypical proximal tibial fractures in adolescents are rare, particularly when linked to hormonal therapy for short stature. This case series reports the clinical and imaging features of atypical proximal tibial and distal femoral physeal fractures in male adolescents undergoing combined growth hormone (GH) and aromatase inhibitor (AI) therapy for idiopathic short stature. We report three cases of skeletally immature male adolescents (ages 12-16) treated with GH and anastrozole who presented with acute leg pain following low-energy trauma during soccer.
View Article and Find Full Text PDFOsteoporos Int
September 2025
Department of Rheumatology, First Faculty of Medicine, Charles University, Katerinska 32, Prague, 121 08, Czech Republic.
Unlabelled: REMS-BMD by radiofrequency echographic multispectrometry is primarily determined by a patient's BMI, age, and sex. Only about 2.8% of the changes in femoral neck REMS-BMD can be attributed to replacement of the total hip with metal implants.
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