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Nightly fasting duration and meal timing are associated with metabolic disorders. This study aimed to investigate the relationships of nightly fasting duration and meal timing with type 2 diabetes mellitus (T2DM) using data from the 2016-2020 Korea National Health and Nutrition Survey. A total of 22,685 adults ≥ 19 years were included in this study. Nightly fasting duration was calculated by subtracting the interval between the day's first and last meal eating times from 24 h. The meal timing were analyzed using various parameters, including the times of the first and last eating episodes and the percentage of energy intake during the morning (05:00 to 9:00 a.m.), evening (06:00 to 09:00 p.m.), and night (after 09:00 p.m.). Men who fasted nightly for ≥ 12 h had lower odds of T2DM (odds ratio (OR): 0.86; 95% confidence interval (CI): 0.75-0.99) than those who fasted for < 12 h. Individuals who had their last meal after 09:00 p.m. had higher odds of T2DM (OR: 1.19, 95% CI: 1.03-1.38, men; OR: 1.19, 95% CI: 1.01-1.40, women). Additionally, the percentage of energy intake during the evening was associated with increased odds of T2DM (OR: 1.41, 95% CI: 1.08-1.84, men; OR: 1.32, 95% CI: 1.02-1.70, women). These findings emphasize the importance of nightly fasting duration and meal timing in modulating the risk of T2DM among Korean adults.
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http://dx.doi.org/10.3390/nu15061385 | DOI Listing |
Breast Cancer Res Treat
August 2025
Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.
Purpose: With limited lifestyle interventions available for women with metastatic breast cancer, we aimed to evaluate feasibility of a combined prolonged overnight fasting and exercise intervention in women with hormone receptor-positive metastatic breast cancer initiating treatment.
Methods: Women with metastatic breast cancer initiating endocrine therapy plus targeted therapy were included in a single-arm pilot trial testing a combined 12-week prolonged nightly fasting and exercise intervention. Fasting goals included abstaining from calorie intake after 8 pm and fasting for 13 + hours 6 days per week; weekly exercise goals were 120 min of home-based aerobic exercise and 2 sessions of resistance exercise.
JCEM Case Rep
September 2025
Children's Hospital Los Angeles and Keck School of Medicine of USC, Department of Pediatrics, Center for Endocrinology, Diabetes and Metabolism, Los Angeles, CA 90027, USA.
The rising prevalence of youth-onset type 2 diabetes (T2D) in children necessitates early intervention with tight glycemic control, obesity medications, and metabolic and bariatric surgery (MBS). Insulin and metformin are standard treatments, but additional therapies for obesity in youth are needed. A 4-year-old Hispanic female with early-onset obesity and newly diagnosed T2D presented with a hemoglobin A1c (HbA1c) level of 8.
View Article and Find Full Text PDFJ Clin Transl Sci
April 2025
Arizona State University, College of Health Solutions, Phoenix, AZ, USA.
Introduction: Cognitive decline and sleep concerns are significant health issues among older adults. Nonpharmacological treatments to address these concerns are needed, particularly for older adults who are more likely to be prescribed multiple medications and experience adverse effects of additional drugs. The aim of the current qualitative study was to understand and document the experiences of older adults with subjective memory decline participating in prolonged nightly fasting (PNF) intervention.
View Article and Find Full Text PDFEur J Nutr
April 2025
Institute of Nutritional and Food Sciences -Nutritional Epidemiology, University of Bonn, Friedrich-Hirzebruch- Allee 7, 53115 Bonn and Heinstück 11, 44225, Dortmund, Germany.
Background: While circadian eating patterns seem to be involved in the aetiology of obesity in adulthood. Little is known about tracking of such patterns from infancy to pre- and primary school age and their prospective impact on body composition.
Methods: Based on data from the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) Study we investigated whether circadian eating patterns in infancy (0-1 years) (1) track to pre- (3-4 years) or primary-school age (6-7 years) and (2) are associated with body composition at primary-school age, using multivariable linear regression models.
J Clin Transl Sci
December 2024
College of Health Solutions, Arizona State University, Phoenix, AZ, USA.
Introduction: Older age significantly increases risk for cognitive decline. A growing number of older adults (≥ 65 years) experience cognitive decline that compromises immediate and/or long-term health. Interventions to mitigate cognitive decline are greatly needed.
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