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http://dx.doi.org/10.1016/j.cgh.2023.03.015 | DOI Listing |
J Prosthet Dent
September 2025
Full Professor, School of Mechanical Engineering, Universidad Industrial de Santander, Bucaramanga, Colombia. Electronic address:
Statement Of Problem: Although custom temporomandibular joint (TMJ) prostheses manufactured via computer-aided design and manufacturing (CAD-CAM) and produced through 3-dimensional (3D) printing or computer numerical control (CNC) allow for sagittal curvature adjustments in the glenoid fossa, their design remains unregulated by the Food and Drug Administration. Consequently, the geometry is determined largely by the engineer's discretion, with limited biomechanical evidence to guide these decisions. The lack of validation regarding how sagittal curvature influences joint stress distribution under various anatomical and functional conditions represents a gap in current knowledge that warrants investigation.
View Article and Find Full Text PDFPhytochem Anal
September 2025
School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China.
Introduction: The drug "alkaloids of Sophora flavescens" (ASF) is an extract from the dried root of S. flavescens Ai. It has various pharmacological effects including anti-arrhythmia, anti-inflammatory, anti-allergic, anti-hepatitis, and antimicrobial.
View Article and Find Full Text PDFJ Biomed Opt
September 2025
Leibniz University Hannover, Hannover Centre for Optical Technologies, Hannover, Germany.
Significance: Melanoma's rising incidence demands automatable high-throughput approaches for early detection such as total body scanners, integrated with computer-aided diagnosis. High-quality input data is necessary to improve diagnostic accuracy and reliability.
Aim: This work aims to develop a high-resolution optical skin imaging module and the software for acquiring and processing raw image data into high-resolution dermoscopic images using a focus stacking approach.
Int J Numer Method Biomed Eng
September 2025
Department of Industrial and Manufacturing Engineering, Pennsylvania State University, University Park, Pennsylvania, USA.
The screw-retained implant-supported crown is a durable, aesthetic restoration, but debonding between the crown and abutment remains a challenge to survivability. The purpose of this work was to devise an abutment shape that can be embedded into the crown while the crown is being additively manufactured. The result was a mechanically retained, no-adhesive abutment and crown unit that is mounted to the implant fixture.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Key Laboratory of Animal Vaccine Development, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. Electronic address:
Group A Rotavirus (RVA) poses a significant health risk. Unfortunately, there are currently no the Food and Drug Administration (FDA) approved antiviral compounds available for treating RVA-induced diarrhea. The lectin-like domain of VP8* plays an important role in the RVA lifecycle.
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