Translating from mouse to man to better understand immune-mediated inflammatory diseases.

Cell Rep Med

Immunology Disease Area and Translational Medicine, Novartis Institutes of BioMedical Research, Basel, Switzerland. Electronic address:

Published: March 2023


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Article Abstract

Lilja et al. explore single-cell transcriptomes across multiple organs of mice with collagen-induced arthritis. They apply network analysis to prioritize functional pathways that support or suppress inflammation and integrate findings with tissue transcriptomics in human immune-mediated inflammatory diseases.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10040445PMC
http://dx.doi.org/10.1016/j.xcrm.2023.100983DOI Listing

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