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(1) Background: The aim of this study was to assess the RV (right ventricle) and LV (left ventricle) Tei index in large for gestational age (LGA) fetuses with a single 360-degree umbilical coil of the umbilical cord around the fetal neck identified by ultrasound in the third trimester of gestation. (2) Methods: The RV and LV Tei index for the cardiac function were measured in 297 singleton pregnancies, and we identified 25 LGA fetuses. There were 48% of LGA fetuses with a nuchal umbilical cord-LGA/NC-larger for gestational age fetuses with a nuchal cord. NC was detected with a color Doppler during a transverse scan of the fetal neck, when the umbilical cord formed a U shape. All fetuses had normal anatomy and normal uterine, placental, umbilical, intracardiac and cerebral Doppler waveforms values for their gestational age. (3) Results: The RV Tei index was significantly higher in the LGA subgroup vs. AGA (0.6 ± 0.2 vs. 0.50 ± 0.2; value = 0.01), but in LGA fetuses with a single coil of the nuchal cord, there were not any significant changes in the Tei indexes. (4) Conclusions: The Tei index might not be impacted by the presence of the nuchal cord in LGA fetuses.
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http://dx.doi.org/10.3390/ijerph20053778 | DOI Listing |
Matern Child Health J
September 2025
Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, 350004, China.
Objectives: To investigate the association between maternal liver enzyme concentrations during pregnancy and the risk of abnormal birth weight.
Methods: This is a prospective birth cohort study querying the pregnant women from Fujian Maternal and Child Health Hospital, affiliated with Fujian Medical University, China. Liver enzyme levels, including gamma-glutamyl transferase (GGT), alanine aminotransferase (ALT), and aspartate aminotransferase (AST), were measured in the first and third trimesters, and changes in liver enzyme levels were calculated based on these measurements.
Pediatr Res
August 2025
Tianjin Women and Children's Health Center, Tianjin, China.
Background: Early gestational weight gain (E-GWG) plays a crucial role in fetal development. Its timing and sex-specific impacts have not been thoroughly investigated, especially in Asian populations.
Methods: In this retrospective cohort study, 66,291 mother-infant pairs from the Tianjin Women and Children's Health Care System were analyzed.
J Ultrasound Med
July 2025
Department of Obstetrics and Gynecology, Division of Perinatology, Ankara Etlik City Hospital, Ankara, Turkey.
Objectives: The aim of this study was to evaluate the association of large for gestational age (LGA) fetuses diagnosed ultrasonographically in the second trimester with adverse perinatal outcomes and to determine the impact of the timing of fetal overgrowth on neonatal outcomes. Accordingly, we investigated whether pregnancies with LGA diagnosed in the second trimester differed in terms of perinatal complications compared to those diagnosed in the third trimester.
Methods: This retrospective cohort study was conducted with pregnant women who presented to the Perinatology Department of Ankara Etlik City Hospital and gave birth to macrosomic fetuses.
Children (Basel)
July 2025
Area of Obstetrics and Gynaecology, Department of Child and Mother Health and Radiology, School of Medicine, University of Cádiz, 11009 Cádiz, Spain.
Pregnancies complicated by idiopathic polyhydramnios are linked to a heightened risk of numerous maternal and perinatal complications. We aim to study the implications of polyhydramnios in term pregnancies complicated with gestational diabetes mellitus (GDM). A prospective cohort study including 340 GDM cases was conducted.
View Article and Find Full Text PDFJ Clin Med
June 2025
Department of Obstetrics and Pathology of Pregnancy, Medical University of Lublin, 20-081 Lublin, Poland.
The Fibroblast Growth Factor (FGF) 19 subfamily plays a key role in the regulation of metabolic and growth processes, and their dysregulation can lead to fetal growth disorders, such as small for gestational age (SGA) and large for gestational age (LGA), as well as to pathogenesis and development of gestational diabetes and gestational hypertension. We conducted a narrative review using the PRISMA2020 statement. Two electronic databases were searched: PubMed and Web of Science until October 2024.
View Article and Find Full Text PDF