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Introduction: The objective of this study was to evaluate the relationship between maxillary transverse deficiency (MTD) diagnosed by 3 methods and molar angulation measured in 3-dimensions in patients with skeletal Class III malocclusion, which could give reference to the selection of diagnostic methods in MTD patients.
Methods: Cone-beam computed tomography data of 65 patients with skeletal Class III malocclusion (mean age 17.35 ± 4.45 years) were selected and imported into MIMICS software. Transverse deficiencies were evaluated by 3 methods, and molar angulations were measured after reconstructing 3-dimensional planes. Two examiners performed repeated measurements to assess the intraexaminer and interexaminer reliability. Pearson correlation coefficient analyses and linear regressions were performed to determine the relationship between a transverse deficiency and molar angulations. One-way analysis of variance was used to compare the diagnostic results of 3 methods.
Results: The novel molar angulation measurement method and 3 MTD diagnostic methods have the interexaminer and intraexaminer intraclass correlation coefficient values >0.6. The transverse deficiency diagnosed by 3 methods was significantly and positively correlated with the sum of molar angulation. There was a statistically significant difference for the transverse deficiencies diagnosed by the 3 methods. The transverse deficiency was significantly higher in Boston University's analysis than in Yonsei's analysis.
Conclusions: Clinicians ought to choose the diagnostic methods properly, considering the feature of the 3 methods and the individual difference of each patient.
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http://dx.doi.org/10.1016/j.ajodo.2022.09.015 | DOI Listing |
Cancer
September 2025
Department of Medical Oncology, Centre Léon Bérard, Lyon, France.
Background: Immune checkpoint inhibitors (ICIs) in unselected sarcomas yield limited response rates and tumor control. Long-term responders have however been reported, suggesting a critical challenge in refining patient selection, by identifying reliable predictive factors for response.
Methods: The authors conducted a multicenter, retrospective study of patients with advanced sarcomas treated with ICIs in six French reference sarcoma centers.
Thromb J
September 2025
C-Care International Hospital Kampala, Plot 4686 Barnabas Road, Kampala, Uganda.
Background: Majority of people with "kissing carotids", an anatomical variation of the cervical carotid arteries showing tortuosity, kinking or coiling and coming in proximity at the midline are asymptomatic. Less than 1% of the general population have Protein S Deficiency. This report discusses a rare case of a young female with co-existent Protein S deficiency and kissing carotids, who presented with sequential thrombosis in both arterial and venous cerebral circulation systems and further discusses potential mechanisms of arterial thrombosis in Protein S deficiency and medical options for secondary stroke prophylaxis in this context.
View Article and Find Full Text PDFActa Odontol Scand
August 2025
Department of Stomatology, Qingdao Jiaozhou Central Hospital, Jiaozhou, China.
Objectives: This study aimed to investigate the effects of rapid maxillary expansion using a Hyrax-type appliance (RME-Hyrax) with anterior traction on the maxillary arch during mixed dentition and its clinical significance, focusing on changes in arch dimensions, occlusal stability, and masticatory function.
Materials And Methods: Forty-two patients with transverse maxillary deficiency were treated with RME-Hyrax, while an untreated control group of 40 received no treatment. Pre- and post-treatment dental casts were analyzed using a 3D scanner.
Medicine (Baltimore)
August 2025
Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Rationale: Hepatoid adenocarcinoma (HAC) is a rare extrahepatic tumor. The most common origin of HAC was the stomach (63%). HACs originating from the colon or rectum are rare.
View Article and Find Full Text PDFJ Hand Surg Eur Vol
August 2025
St John's Hospital, UK.
The aim of this study was to explore the pattern of eye dominance in individuals with congenital transverse absences between humeral and metacarpal levels. Eighty-one patients were included with a median age of 25 years (interquartile range 15 to 35; range 6-71). The left-right laterality of limb absence was 27:54.
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