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Abundant evidence shows that consolidated memories are susceptible to modifications following their reactivation. Processes of memory consolidation and reactivation-induced skill modulation have been commonly documented after hours or days. Motivated by studies showing rapid consolidation in early stages of motor skill acquisition, here we asked whether motor skill memories are susceptible to modifications following brief reactivations, even at initial stages of learning. In a set of experiments, we collected crowdsourced online motor sequence data to test whether post-encoding interference and performance enhancement occur following brief reactivations in early stages of learning. Results indicate that memories forming during early learning are not susceptible to interference nor to enhancement within a rapid reactivation-induced time window, relative to control conditions. This set of evidence suggests that reactivation-induced motor skill memory modulation might be dependent on consolidation at the macro-timescale level, requiring hours or days to occur.
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http://dx.doi.org/10.1038/s41598-023-29963-5 | DOI Listing |
JAMA Netw Open
September 2025
Social and Behavioral Sciences Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Importance: Higher intellectual abilities have been associated with lower mortality risk in several longitudinal cohort studies. However, these studies did not fully account for early life contextual factors or test whether the beneficial associations between higher neurocognitive functioning and mortality extend to children exposed to early adversity.
Objective: To explore how the associations of child neurocognition with mortality changed according to the patterns of adversity children experienced.
Disabil Rehabil Assist Technol
September 2025
Department of Special Needs Education and Rehabilitation, Department Pedagogy and Didactics for People with Physical and Motor Development Impairments and Chronic and Progressive Illnesses, Carl von Ossietzky University, Oldenburg, Germany.
Objectives: Many studies investigate the impact of assistive devices and technologies (AD/AT) on physical outcomes. The role of AD/ATs in everyday activities and participation of children with cerebral palsy (CP) has received much less attention. This review scopes the impact of AD/ATs by the activities and participation components of the International Classification of Functioning, Disability and Health (ICF) model.
View Article and Find Full Text PDFCereb Cortex
August 2025
Faculty of Psychology and Education Science, Department of Psychology, University of Geneva, Chemin des Mines 9, Geneva, 1202, Switzerland.
Language learning and use relies on domain-specific, domain-general cognitive and sensory-motor functions. Using fMRI during story listening and behavioral tests, we investigated brain-behavior associations between linguistic and non-linguistic measures in individuals with varied multilingual experience and reading skills, including typical reading participants (TRs) and dyslexic readers (DRs). Partial Least Square Correlation revealed a main component linking cognitive, linguistic, and phonological measures to amodal/associative brain areas.
View Article and Find Full Text PDFQual Life Res
September 2025
The Kids Research Institute Australia, The University of Western Australia, P.O. Box 855, West Perth, WA, 6872, Australia.
Purpose: CDKL5 deficiency disorder (CDD) is a rare developmental and epileptic encephalopathy. Greater understanding of the smallest meaningful improvements for individuals with CDD in clinical trials and practice is needed for a person-centred approach to treatment efficacy. This study explored how parent/caregivers of people with CDD understood meaningful improvements and described change for priority functional domains including communication, gross motor, fine motor, feeding.
View Article and Find Full Text PDFS Afr J Commun Disord
August 2025
Department of Speech-Language Pathology and Audiology, Faculty of Humanities, University of Pretoria, Pretoria.
Background: Small infants face more developmental risks than their full-term peers, necessitating early intervention and long-term monitoring.
Objectives: This study examined the longitudinal developmental and hearing outcomes of small infants attending a high-risk clinic in a South African low-income community setting.
Method: A short-term longitudinal within-subject descriptive study design was employed, where 28 participants underwent hearing and developmental screenings and assessments at two follow-up appointments (T1 and T2), at 6- and 12-month corrected age.