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http://dx.doi.org/10.1016/S2213-2600(23)00042-5 | DOI Listing |
J Safety Res
September 2025
Department of Emergency Medicine, University of British Columbia, Vancouver General Hospital, Vancouver, BC, Canada. Electronic address:
Introduction: Older adults are increasingly involved in motor vehicle collisions (MVCs). Hypnotics are known to impair driving ability. This study investigated the prevalence of hypnotics use among older adult drivers involved in MVCs and evaluated their impact on injury severity and co-prevalence with other central nervous system (CNS) depressants.
View Article and Find Full Text PDFCan Vet J
September 2025
Emergency and Critical Care Department, New River Veterinary Specialists, 600 Argent Boulevard, Hardeeville, South Carolina 29927, USA (Graeber); Emergency and Critical Care Department, Veterinary Emergency and Critical Care, 8650 W. Tropicana Avenue B107, Las Vegas, Nevada 89147, USA (Weatherton).
Our objective was to describe a case of suspected relay barbiturate intoxication of a dog after ingestion of a rat that had been euthanized and frozen and then later burned in an attempted cremation. This case will be compared to previous reports of relay toxicosis. This report describes a dog that was presented to an emergency and critical care hospital because of lethargy and vomiting after ingesting remains of a rat that had been euthanized 2 wk earlier.
View Article and Find Full Text PDFDrug Des Devel Ther
September 2025
Department of Anesthesiology, The Second People's Hospital of Guiyang, The Affiliated Jinyang Hospital of Guizhou Medical University, Guiyang, People's Republic of China.
Background: Remimazolam tosilate, a novel ultra-short-acting benzodiazepine, demonstrates promising safety profiles in clinical settings. While both remimazolam tosilate and etomidate provide hemodynamic stability during anesthesia induction, limited research has directly compared their effects on electroencephalogram (EEG) burst suppression (periods of transient brain wave silence), a potential predictor of adverse neurological outcomes. This study aims to compare the incidence rate of EEG burst suppression (ESR) with remimazolam tosilate versus etomidate by reviewing the drug regimens used by different anesthesiologists in clinical practice.
View Article and Find Full Text PDFCureus
August 2025
Department of Internal Medicine, University at Buffalo, Buffalo, USA.
Asthma is one of the most prevalent chronic respiratory illnesses, significantly impacting patients through shortness of breath and even death. Acute exacerbations are usually controlled with a short-acting beta agonist, such as an albuterol inhaler, as well as long-acting agents to prevent the occurrence of exacerbations and status asthmaticus. Status asthmaticus is an emergent episode of asthma that is refractory to standard treatment.
View Article and Find Full Text PDFBMC Pulm Med
September 2025
Division of Cellular Pneumology, Priority Area Infections, Research Center Borstel, Leibniz Lung Center, Borstel, 23845, Germany.
Background: Volatile anesthetics are gaining recognition for their benefits in long-term sedation of mechanically ventilated patients with bacterial pneumonia and acute respiratory distress syndrome. In addition to their sedative role, they also exhibit anti-bacterial and anti-inflammatory properties, though the mechanisms behind these effects remain only partially understood. In vitro studies examining the prolonged impact of volatile anesthetics on bacterial growth, inflammatory cytokine response, and surfactant proteins - key to maintaining lung homeostasis - are still lacking.
View Article and Find Full Text PDF