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The ever-increasing global energy demand has led world towards negative repercussions such as depletion of fossil fuels, pollution, global warming and climate change. Designing microbial cell factories for the sustainable production of biofuels is therefore an active area of research. Different yeast cells have been successfully engineered using synthetic biology and metabolic engineering approaches for the production of various biofuels. In the present article, recent advancements in genetic engineering strategies for production of bioalcohols, isoprenoid-based biofuels and biodiesels in different yeast chassis designs are reviewed, along with challenges that must be overcome for efficient and high titre production of biofuels.
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http://dx.doi.org/10.1016/j.biortech.2023.128668 | DOI Listing |
Prep Biochem Biotechnol
September 2025
Biofuels Institute, School of Environment & Safety Engineering, Jiangsu University, Zhenjiang, China.
Lactic acid bacteria (LAB) are widely used in industrial fermentation due to their versatile metabolic capabilities. This study investigated the molecular mechanisms underlying organic acid biosynthesis in newly isolated YC1-1-4B and PC-C1 strains at two culture intervals and their applications in corn biomass fermentation. YC1-1-4B exhibited faster growth and higher organic acid production (29.
View Article and Find Full Text PDFAppl Environ Microbiol
September 2025
Biofuels Institute, School of Emergency Management, School of the Environment and Safety Engineering, Jiangsu University, Zhenjiang, Jiangsu, PR China.
is a thermophilic acetogenic bacterium capable of thriving at elevated temperatures up to 66°C. It metabolizes carbohydrates such as glucose, mannose, and fructose and can also grow lithotrophically utilizing hydrogen (H) and carbon dioxide (CO) or carbon monoxide (CO), with acetate serving as its main product. A simple and efficient genome editing system for would not only facilitate the understanding of the physiological function of enzymes involved in energy and carbon metabolism but also enable metabolic engineering.
View Article and Find Full Text PDFRecent Pat Biotechnol
August 2025
Department of Life Sciences, J.C. Bose University of Science and Technology, YMCA, Faridabad, Haryana-121006, India.
Introduction: The production of bio-oil from microalgae is gaining attention as an alternative renewable energy source. To generate advances in this field, it is essential to identify the gaps in existing research. Overcoming this barrier necessitates addressing methodologies that can assess the existing work and develop relationships between publications, research groups, and their impact.
View Article and Find Full Text PDFBiochim Biophys Acta Proteins Proteom
September 2025
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Malhaur Station Road, Lucknow 226028, India; Research Cell, Amity University Uttar Pradesh, Lucknow Campus, Malhaur Station Road, Lucknow 226028, India. Electronic address:
Scenedesmus quadricauda, a freshwater microalga, has gained attention for its high lipid accumulation potential. However, information on fatty acid (FA) biosynthesis pathways in Scenedesmus species remains limited. Biomass (1.
View Article and Find Full Text PDFJ Colloid Interface Sci
August 2025
State Key Laboratory of Green Biomanufacturing, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.; Key Laboratory of Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China.; Ordos Laboratory, Inner
Currently, electrocatalytic conversion of carbon dioxide into higher-value compounds is a promising approach. However, developing a stable and efficient catalyst with high selectivity for specific products remains a major challenge. Herein, we constructed a bismuth-based metal-organic framework (Bi-MOF) as a catalyst for the catalytic production of formic acid from carbon dioxide, to which different ratios of tin metal elements were doped.
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